The Cardiac Conduction System

Auteur
Dr. Jensen is an Assistant Professor, in the Department of Medical Biology, at the University of Amsterdam. His research focus is cardiac evolution from fish to man. He also studies expression of genes, development, anatomy, and physiology. He is interested in the evolutional conservation of the building plan of the heart, in the rich variation of cardiac chambers, septa, and architecture. Dr. Bas Boukens is an Associate Professor in the Department of Physiology at Maastricht University. He has researched and studied arrhythmogenic remodeling in explanted human hearts and dynamics of ventricular fibrillation in sheep. He's also investigated the mechanism of arrhythmias in J-wave syndromes, the role of autonomic nervous system in cardiac repolarization and in mechanisms of arrhythmias resulting from acute ischemia.

Texte du rabat
The Cardiac Conduction System: Evolution, Development, and Therapeutic Potential provides the reader a thorough and comprehensive review of this intricate system. The book covers conventional topics: anatomy, electrophysiology, and key cellular characteristics, as well as emerging topics: patient specific computer modelling, induced pluripotent stem cells, and in vivo editing as state-of-the-art treatment strategy. Given the exhaustive coverage of topics, this book will likely become the "go-to reference" for the cardiac conduction system for years to come. This is a volume in Elsevier’s new series Hot Topics in Physiology, published in association with the International Union of Physiological Sciences (IUPS). It **is an ideal reference for academics and researchers in anatomy, physiology, cardiology, electrophysiology, biomedical engineering and medical education at Undergrad, Masters, PhD, and Post-Doc levels.

Contenu

Part 1 Introduction 1. Defining the Conduction System Part 2 Development and Evolution 2. History of the Cardiac Conduction System 3. Development of the Cardiac Conduction System 4. Regulatory Networks in the Cardiac Conduction System 5. Cardiac Conduction System in Mammals 6. Cardiac Conduction System in Non-Mammalian Vertebrates Part 3 Electrophysiology 7. Electrophysiology of the Sinus Node 8. Electrophysiology of the Atrioventricular Node 9. His Bundle, Bundle Branches, Purkinje Cells 10. Autonomic Modulation of the Conduction System Part 4 Disease and Treatment 11. Conduction System Diseases and Mechanism of Arrhythmias 12. The Therapeutic Potential of Conduction System Pacing 13. Modeling of the Cardiac Conduction System 14. Building and Repairing the Cardiac Conduction System 15. Corrective Surgery and the Conduction System