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The Latest Research Findings
on Androgen Excess Disorders in Women
A thoroughly revised and comprehensive edition of a highly praised classic, Androgen Excess Disorders in Women covers the growing importance of polycystic ovary syndrome (PCOS) as the most prevalent androgen excess disorder in women. This volume addresses the latest research findings on the etiology, pathophysiology, clinical manifestations, genetics, and consequences of androgen excess disorders in women, including PCOS, non-classic adrenal hyperplasia, androgen-secreting tumors, severe insulin-resistant hyperandrogenic syndromes, and rarer causes of androgens excess and hirsutism.
Includes supplementary material: sn.pub/extras
Contenu
A Brief History of Androgen Excess.- Physiology of Androgens.- Ovarian and Adrenal Androgen Biosynthesis and Metabolism.- Androgens Throughout the Life of Women.- Physiological Effects of Androgens in Women.- Androgen Measurements.- Uncommon Causes of Androgen Excess.- Androgen-Secreting Adrenal and Ovarian Neoplasms.- Cushing's Syndrome, Acromegaly, and Androgen Excess.- The Nonclassic Adrenal Hyperplasias.- Pregnancy-Related Androgen Excess.- Drug-Induced Hyperandrogenism.- Severe Insulin-Resistance Hyperandrogenic Syndromes.- Idiopathic Hirsutism.- The Polycystic Ovary Syndrome.- Definition and Epidemiology of the Polycystic Ovary Syndrome.- Clinical Features of the Polycystic Ovary Syndrome.- Biochemical Features of the Polycystic Ovary Syndrome.- Ovarian Histology, Morphology, and Ultrasonography in the Polycystic Ovary Syndrome.- Hypothalamic-Pituitary-Gonadotropic Dysfunction in the Polycystic Ovary Syndrome.- Ovarian Steroidogenic Abnormalities in the Polycystic Ovary Syndrome.- Hypothalamic-Pituitary-Adrenal Dysfunction in the Polycystic Ovary Syndrome.- The Genetic Basis of the Polycystic Ovary Syndrome.- Pediatric Hyperandrogenism and the Polycystic Ovary Syndrome in Adolescence.- Environmental Factors in the Polycystic Ovary Syndrome.- Animal Models and Fetal Programming of the Polycystic Ovary Syndrome.- Insulin Resistance and Hyperinsulinism in the Polycystic Ovary Syndrome.- The Endocrine Impact of Obesity and Body Habitus in the Polycystic Ovary Syndrome.- Molecular Mechanisms of Insulin Resistance in the Polycystic Ovary Syndrome.- Menstrual Dysfunction and Endometrial Neoplasia in the Polycystic Ovary Syndrome and Other Androgen Excess Disorders.- ?-Cell Dysfunction, Glucose Intolerance, and Diabetes in the Polycystic Ovary Syndrome.- Hypertensionand Cardiovascular and Lipoprotein Abnormalities in the Polycystic Ovary Snydrome.- Reproductive and Obstetrical Consequences of the Polycystic Ovary Syndrome.- Psychosocial and Quality-of-Life Consequences of Androgen Excess and the Polycystic Ovary Syndrome.- Overview of Long-Term Morbidity and Economic Cost of the Polycystic Ovary Syndrome.- Evaluation and Treatment of Androgen Excess.- Clinical and Hormonal Evaluation of Androgen Excess.- Ovarian Suppression and Treatment of Hirsutism.- Polycystic Ovary Syndrome and Ovulation Induction.- In Vitro Fertilization for the Polycystic Ovary Syndrome.- Surgical Management of the Polycystic Ovary Syndrome.- Use of Insulin Sensitizers in the Polycystic Ovary Syndrome.- Weight Reduction and Lifestyle Modifiction in the Treatment of Androgen Excess.
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