Regenerative Hepatology and Liver Transplantation: Volume 2

Auteur
Dr. Paulo Martins is an Associate Professor of Surgery at University of Massachusetts. Since 2013, Dr. Martins has been working as a transplant Surgeon at the University of Massachusetts and principal investigator at a transplant laboratory in the same institution. During his career he has obtained several research awards and grants and in 2015, he was indicted fellow of the American Society of Transplantation and 2017 fellow of the American College of Surgeons. He has worked on experimental surgery since medical school and has focused his research on ischemia reperfusion injury and donor/graft modulation using small and large animal transplant models. Dr. Martins has trained microsurgeons and supervised several graduate students, residents, PhD students in the hospital and in his laboratory. He is an editorial board member of 3 scientific journals, ad-hoc reviewer of 10 medical journals, committee member of several organizations and member of 6 scientific/professional associations. Dr. Pedro Baptista is originally from Portugal, where he graduated from the School of Pharmacy of the University of Lisbon. He completed his doctoral dissertation at the Gulbenkian Ph.D. Program in Biomedicine. He is currently a Group Leader at the Health Research Institute of Aragon in Zaragoza, Spain and the founder of the Organ Bioengineering and Regenerative Medicine Laboratory at this institution. He is also an Assistant Professor at the Department of Biomedical and Aerospace Engineering at University Carlos III of Madrid, Spain. He is one of the founders and the Deputy Chairman of the European Association for the Study of the Liver Consortium for Regenerative Hepatology and currently the Deputy Secretary General and an elected Board Governor of the European Society for Artificial Organs. His current research focuses on creating bioengineered livers that can finally make the long-term transplantation of these lab-grown organs a reality.Dr. Pedro Baptista is originally from Portugal, where he graduated from the School of Pharmacy of the University of Lisbon. He completed his doctoral dissertation at the Gulbenkian Ph.D. Program in Biomedicine. He is currently a Group Leader at the Health Research Institute of Aragon in Zaragoza, Spain and the founder of the Organ Bioengineering and Regenerative Medicine Laboratory at this institution. He is also an Assistant Professor at the Department of Biomedical and Aerospace Engineering at University Carlos III of Madrid, Spain. He is one of the founders and the Deputy Chairman of the European Association for the Study of the Liver Consortium for Regenerative Hepatology and currently the Deputy Secretary General and an elected Board Governor of the European Society for Artificial Organs. His current research focuses on creating bioengineered livers that can finally make the long-term transplantation of these lab-grown organs a reality.

Texte du rabat
Regenerative Hepatology and Liver Transplantation is the second volume in the Regenerative and Transplant Medicine series. This volume is essential as no field in the biomedical sciences has more interest than organ transplantation regarding regenerative medicine, primarily because of the urgent need to improve transplant outcomes and increase transplantation rates is critical to treat the many patients suffering from liver disease.
The goal of this book is to bridge regenerative hepatology and transplant medicine, by illustrating the state of the art of clinical liver transplantation, as well as of the progress of regenerative medicine (RM) investigations aiming at the bioengineering, regeneration, and repair of the liver.

This volume is necessary and would be placed well in the current global trend toward increasing organ donation utilizing such cutting-edge technologies. Written by the world’s experts in the field of liver diseases, it is a perfect reference for transplant operators, researchers, regenerative medicine operators, tissue engineering operators, biotech operators, and those in academia, industry, and regulatory agencies working to advance the field.

Contenu

1. Prevalence of liver disease around the world
2. Viral Hepatitis
3. Non-alcoholic steatohepatitis
4. Alcoholic liver disease
5. Liver fibrosis/cirrhosis
6. Biomarkers in liver disease and transplantation: Outlook for precision medicine
7. Living donor Liver Transplantation
8. Small-for-size syndrome in Liver transplantation
9. Clinical trials design and endpoints in liver transplantation
10. Oncologic liver Transplantation
11. Hepatocellular carcinoma Management
12. Human Hepatocyte Transplantation
13. Mesenchymal Stem Cell Transplantation
14. Biliary Tree Stem Cell Transplantation
15. General Principles of Organ Preservation in Liver transplantation
16. Ischemia-Reperfusion injury
17. Liver Regeneration
18. Liver Bioengineering (file incomplete)
19. Nanotechnology application in Liver Transplantation
20. Acute Liver Failure and Bioreactors/Liver Assist devices
21. Hepatobiliary Organoids and Large-Scale Expansion for Regenerative Therapies
22. Liver aging