Progress in Tryptophan and Serotonin Research

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Frontmatter -- Preface -- CONTENTS -- OPENING SESSION -- Adolf Butenandt's Work on the Metabolism of Tryptophan / Biekert, E. -- Tryptophan, the Heart of the Toxic Peptides from Amanita Mushrooms / Wieland, Th. -- Forty Years of Trypto-Fun / Witkop, Bernhard -- Indoleamine Dioxygenase - a Possible Biological Function / Hayaishi, Osamu / Yoshida, Ryotaro / Takikawa, Osamu / Yasui, Hiroaki -- QUALITATIVE AND QUANTITATIVE ANALYSIS OF TRYPTOPHAN AND ITS METABOLITES -- Liquid Chromatography/Electrochemistry Determination of Biogenic Amines: Improved Performance Using Low Dead Volume Multiple Electrode Transducers / Kissinger, P. T. -- GLC and HPLC Analysis of Tryptophan, Kynurenine and Related Metabolites / Joseph, M. H. -- Monitoring of Tryptophan Levels in Biological Fluids by HPLC: An Improved Method / Bettero, Antonio / Costa, Carlo / Allegri, Graziella -- Rapid Determination of Tryptophan and its Metabolitesalong the Kynurenine Pathway by HPLC / Costa, Carlo / Bettero, Antonio / Allegri, Graziella -- HPLC-Analysis of Xanthurenic Acid and its 8-Methyl-Ether / Schrijver, Jaap / Schaik, Frank van / Greef, Jan van der / Bos, Klaas D. / Schreurs, Wil H. P. -- Free and Total Tryptophan Microdetermination by an Automated Fluorometric Method / Bigot, Jean-Claude / Moineau, Marie-Pierre / Menez, Jean-François / Bardou, Louis-Georges -- Comparison of HPLC and GC-MS Methods for the Determination of Tryptophan and its Indole Metabolites in Biological Samples / Martínez, Emili / Adell, Albert / Suñol, Cristina / Artigas, Francesc / Tusell, Josep M. / Gelpí, Emili -- Pineal Indoles: Their Determination by High Performance Liquid Chromatography and the Influence of Diurnal Variation and Tryptophan Administration on their Level in the Rat / Young, Simon N. / Anderson, George M. -- Higher-Order Derivative Spectrophotometry for the Quantitative Determination of Tryptophan, Tyrosine and Phenylalanine in Two- and Three-Component Mixtures, Peptides and Proteins / Talsky, Gerhard / Tichy, Sibylle -- The Application of a Spectrofluorometer-Optical- Multichannel Analyzer System to the Determination of Tryptophan / Steinhart, Hans / Stützle, Petra -- Picomole Determination of Tryptophan by Derivatization to 9-Hydroxymethyl-ß-Carboline / Takai, Katsuji / Inoue, Shintaro -- Determination of Tryptophan in Food after Alkaline Hydrolysis: An Evaluation / Nielsen, Henrik K. / Hurrell, Richard F. -- Colorimetric Determination of Tryptophan in Corn-Cob Mix (CCM) / Votisky, Erika -- Comparison of Tryptophan Assays for Food Proteins / Friedman, Mendel / Levin, Carol E. / Noma, Amy T. / Montague, William C. / Zahnley, James C. -- WORKSHOP: ANALYSIS OF TRYPTOPHAN -- Discussion at the Workshop on "Analysis of Tryptophan" / Friedman, Mendel -- TRYPTOPHAN AND SEROTONIN: NEUROBIOLOGY -- Tryptophan Transport to the Brain: Newer Findings and Older Ones Reconsidered / Curzon, G. / Sarna, G. S. -- Tryptophan Availability and Serotonin Synthesis in Rat Brain: Effects of Experimental Diabetes / Fernstrom, John D. -- Anatomy and Function of Central Serotoninergic Neurons / Baumgarten, Hans Georg / Schlossberger, Hans Georg -- Serotonin Receptor Binding Sites: Localization and Role in the Brain and Peripheral Tissues / Leysen, Josée E. -- Involvement of 5-HT2 (S2)- Receptor Sites in the Serotonin-Induced Activation of Cat Platelets / De Clerck, Fred / Xhonneux, Benoit / Gommeren, Walter / Leysen, Josée -- The Regulation of 5-Hydroxytryptamine Release from Superfused Synaptosomes by Tryptophan / Suter, Hugh A. / Collard, Keith J. -- Selective Increases in High Affinity Tryptophan Transport in Synaptosomes from Different Brain Areas Incubated in Sodium-Free Media / Wilkinson, Lawrence S. / Price, Christopher J. / Collard, Keith J. -- Formation and Function of Tetrahydro-ß-Carbolines with Special Reference to their Action on [3H] - Tryptamine Binding Sites / Rommelspacher, H. / Brüning, G. -- Regulations of Serotonergic Neurons Innervating the Basal Ganglia: In vivo Release Studies / Glowinski, J. / Soubrié, P. -- Blood Platelets as Models for Neurons: Similarities of the 5-Hydroxytryptamine Systems / Pletscher, Alfred / Affolter, Hubert / Cesura, Andrea M. / Erne, Paul / Müller, Kurt -- In vivo Metabolism of 14C-5-HT, 14C-5.6-DHT and 14C-5.7-DHT by MAO/COMT/Aldehyde Dehydrogenase in Rat Brain / Baumgarten, Hans Georg / Klemm, Hans Peter / Schlossberger, Hans Georg -- Tryptophan Metabolism in the Pineal Gland / Reiter, Russel J. -- Some Physiological Responses and Effects of the Pineal Indoleamine Melatonin / Arendt, Josephine -- Pharmacologic Regulation of Serum N-Acetylserotonin / Brown, Gregory M. / Burns, Timothy G. / Psarakis, Stella / Grota, Lee J. -- N-Acetyltryptophan: Biochemical and Pharmacological Studies / Garnier, Jean-Pierre / Escande, Christine / Bousquet, Bernard / Tran, Gilles / Dreux, Claude -- Serotonin, a Major Metabolite of Tryptophan in the Rabbit Retina / Osborne, Neville N. / Patel, Saraswati / Beaton, David W. -- Effect of 5-Hydroxyanthranilic Acid on Arachidonate Metabolites Function in Platelet Aggregation System / Goda, Kiyoshi / Mori, Terutoshi / Ueda, Takashi / Kotake, Yahito -- WORKSHOP: CLINICAL AND BEHAVIOURAL EFFECTS OF TRYPTOPHAN -- Introduction to Workshop / Hartmann, E. -- Tryptophan and Human Sleep: An Analysis of 43 Studies / Hartmann, Ernest / Greenwald, Daniel -- L-Tryptophan in Chronic Insomnia / Nedopil, Norbert / Einhäupl, Karl / Rüther, Eckart / Steinberg, Reinhard -- Tryptophan (500 mg) Decreases Subjectively Perceived Sleep Latency and Increases Sleep Depth in Man / Leathwood, Peter / Pollet, Patricia -- Further Evidence of the Hypnotic Properties of Tryptophan / Lieberman, Harris R. / Corkin, Suzanne / Wurtman, Richard J. -- The Therapeutic Action of Tryptophan in Depression, Mania, and Aggression / Young, S. N. / Chouinard, G. / Annable, L. / Morand, C. / Ervin, F. R. -- The Effects of Dietary Tryptophan on Chronic Maxillofacial Pain Tolerance / Seltzer, Samuel / Pollack, Robert L. / Dewart, Dorothy / Jackson, Eric -- PATHOLOGY, CLINICAL ASPECTS -- Modulation of Serotonin Receptors by L-Valine in Hepatic Encephalopathy / Kienzl, E. / Riederer, P. / Jellinger, K. / Roth, E. / Ferenci, P. -- Effect of a B-Vitamin on Tryptophan Metabolism in South African Bantu with Pellagra / Hankes, L. V. / Jansen, C. R. / De Bruin, E. P. / Schmaeler, M. -- Studies on the Urinary Excretion of Xanthurenic Acid in Diabetics / Hattori, Masayasu / Kotake, Yazo / Kotake, Yahito / Otsuka, Hidetsugu / Shibata, Yukio -- Urinary Excretion of Xanthurenic Acid and Zinc in Diabetes / Ikeda, Sayoko / Kotake, Yahito -- Studies of the Clinical Importance and Molecular Defect of Hereditary Vitamin B6 Dependent Xanthurenic Aciduria / Knapp, Alwin / Grimm, Ulrich -- Tryptophan - Nicotinic Acid Pathway in Cardiovascular Diseases / Rudzite, Vera / Sileniece, Gunta / Jirgensons, Jánis -- The Dependence of Stress Induced Increases in Functional 5HT Activity on Increased Tryptophan Availability: Evidence that in vivo Electrochemistry Monitors 5-Hydroxyindole Release / Joseph, Michael H. / Kennett, Guy A. -- Increased Availability of Tryptophan to the Brain in Stress is not Mediated via Changes in Competing Amino Acids / Joseph, M. H. / Johnson, J. A. / Kennett, G. A. -- Free and Bound Plasma Tryptophan Levels in Psychiatric Disorders / Agarwal, D. P. / Ziemsen, B. / Goedde, H. W. / Philippu, G. / Milech, U. / Schrappe, O. -- Cerebrospinal Fluid 5HIAA and Tryptophan in Depression and Suicide / Banki, Csaba M. / Aratô, Mihâly / Papp, Zsuzsa / Kurcz, Mihâly -- The Influence of L5-Hydroxytryptophan (L5-HTP) on Clinical and Biochemical Parameters in Depressive Patients / Raba, M. / Riederer, P. / Danielczyk, W. / Seemann, D. -- Plasma Tryptophan Levels and 5-Hydroxytryptamine Synthesis in the Brain and the Spinal Cord in "Arthritic" Rats / Weil-Fugazza, Jeanne / Godefroy, Françoise / Bineau-Thurotte, Magali / Besson, Jean-Marie -- Effects of Antirheumatic Drugs and Tricyc…