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This book shows the huge impact the gut microbiota has on the gastrointestinal health of humans with a particular focus on children. It also highlights the potential use of probiotic microorganisms to protect or improve children's gastrointestinal health.
Humans are not single organisms: We are a multi-organism structure composed of ourselves and our microbiota, living in close symbiosis since birth and even before. The huge impact that the billons of microscopic cells living in our gut have on our gastrointestinal and systemic health cannot be overestimated. The enormous progress that has been made in the past decade in our still very incomplete understanding of the gut microbiota is opening the door to potential applications in human health that were simply unthinkable before.
One of the most interesting aspects of this new scientific horizon is the fact that we may identify (or even create in the laboratory) and utilize many of these friendly bacteria to protect, or improve our health. Thus, strains of probiotic microorganisms are being identified and studied in a vast array of clinical scenarios. Among the most investigated areas for probiotics is the gastrointestinal health of children. The topics addressed in this book are spanning from the development of the gut microbiota in the fetus and newborn all the way to current and potential applications in disparate conditions such as necrotizing enterocolitis, or infectious, or inflammatory conditions affecting the child.
The book is written in a rigorous, evidence based manner by an international group of outstanding experts in these fields and is aimed at pediatric gastroenterologists, pediatricians and physician scientists alike.
Highlights impact of gut microbiota on gastrointestinal and systemic health Shows current and potential applications of probiotics in disparate conditions of children Addresses gut microbiota and conditions spanning from newborn to infant and child
Auteur
Stefano Guandalini, MD
Professor Emeritus and Chief,
Founder and Medical Director, Celiac Disease Center
University of Chicago, USA
Indrio Flavia, MD
Department of Pediatrics
University of Bari "Aldo Moro", Italy
Résumé
"This book is geared toward those in clinical practice who wish to provide the highest level of care to their patients. ... readers with at least a basic appreciation of microbiology will get the most out of this book. ... There is no doubt that reading this book will prepare clinicians interested in probiotic therapy to use this modality more judiciously, to the benefit of those in their care." (Joseph Runde, Doody's Book Reviews, October 25, 2019)
Contenu
From the contents: 1. The newborn.- Microbiota development of newborns starts in utero.- Pathogenesis and possible prevention of Necrotizing Enterocolitis.- Can post-biotics represent a new strategy for NEC? - 2. The Infant.- Preventing and treating colics.- Food Allergy prevention.- Can celiac disease be prevented with probiotics? 3. The child.- Fighting fatty liver with probiotics.- Inflammatory Bowel Disease.- Acute Infectious Diarrhea.- Functional GI disorders.- Clostridium difficile colitis prevention and treatment.