Pharmaceuticals from Microbes

This book has been assembled with the hope of being an authoritative, comprehensive, conceptually sound and highly informative compilation of recent advances describing the concepts of bioengineering in the field of microbiology. It comprises of seven chapters written by eminent authors in their respective fields. Topics included deal with the significant advancement of microbial technology with emphasis on drug delivery strategies for healthcare products, vaccine delivery, biotransformation approaches to generate new molecules, upstream/downstream processing of biopharmaceuticals. It serves as excellent reference material for researchers, students and academicians in the fields of biotechnology, microbiology and pharmaceutical sciences.

Explores the critical aspects of innovative strategies for microbial products in academia and healthcare industry Covers the use of genetically modified bacteria for the delivery of vaccine antigens Describes the polymeric particle based bioactive delivery systems against microbes Emphasises the significance of engineered new molecules and biotransformation approaches using microbial platforms Highlights process technology related to the upstream/downstream processing of biopharmaceuticals

Contenu

1. Advances in drug delivery strategies for microbial healthcare products.- 2. Live-attenuated bacterial vectors for delivery of mucosal vaccines, DNA vaccines and cancer immunotherapy.- 3. Poly lactide/poly lactide-co-glycolide based delivery system for bioactive compounds against microbes.- 4. Drug delivery systems based on pullulan polysaccharides and their derivatives.- 5. Microbial modifications of flavonols.- 6. Downstream processing for biopharmaceuticals recovery.- 7. Engineering Streptomyces peucetius for doxorubicin and daunorubicin biosynthesis.