RNA: Computational Methods for Structure, Kinetics, and Rational Design: Volume One

Auteur

Peter Clote is Professor of Biology at Boston College, USA, with courtesy appointment in Computer Science. He is an international expert in computational biology, with focus on RNA. Earning B.Sc. and PhD degrees in mathematics from MIT and Duke University, as well as a Doctorat d'Etat from Université Paris 7, Clote has held faculty positions in mathematics, computer science, and biology departments at universities in France (Paris 7), the United States (BC), and Germany (LMU). As Gentzen Chair of Computer Science at the University of Munich (LMU), he played a leading role in the establishment of the bioinformatics graduate program there. He has held visiting positions at MIT, the Max Planck Institute in Berlin, CWI in Amsterdam, Ecole Polytechnique and Université Paris-Sud (as Digiteo Chair of Excellence in Computer Science), and other universities. Clote started and co-organized the MIT Bioinformatics Seminar over a period of ten years, he has served as Associate Editor of the Journal of Mathematical Biology, on the editorial board of four other journals, and has co-written two books, co-edited four books, and published around 100 research articles in computational biology, mathematics, and theoretical computer science. His research was and continues to be supported by NSF divisions of mathematical sciences, biology, and computer science, as well as by Digiteo (France) and DFG (Germany). He has received a Fulbright and a Guggenheim fellowship, as well as receiving an Alexander von Humboldt Foundation research grant.

Texte du rabat

RNA Structure, Kinetics, and Rational Design is a comprehensive treatment of computational methods concerning the secondary structure, folding kinetics and rational design of RNA. This book provides the nuts, bolts and tools to take the next steps in computational RNA synthetic biology.

Contenu

Chapter 1 RNA biology. Chapter 2 Thermodynamics. Chapter 3 RNA energy parameters. Chapter 4 Combinatorics. Chapter 5 Algorithms