Principles of Computational Genomics

Auteur

Paolo Provero obtained his PhD in Theoretical Physics in 1992. Since 2000, his research focuses on computational genomics, and in particular on the evolution and variation of gene expression and gene regulation. He is currently Full Professor of Molecular Biology at the University of Turin, Italy.

Texte du rabat

The main focus is on the analysis of next-generation-sequencing assays, both for the interpretation of the DNA sequence per se and for the study of gene regulation and epigenomics.

Contenu

Chapter 1 Sequence alignment and phylogenetics

Chapter 2 Transcriptomics, part I: class comparison

Chapter 3 Transcriptomics, part II: class discovery and enrichment analysis

Chapter 4 Transcriptomics, part III: single-cell RNA-sequencing

Chapter 5 Transcriptional regulation

Chapter 6 Variation and phenotype

Bibliography

Index