Oxidative Stress in Lung Diseases

This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.

Covers the major lung diseases mediated by oxidative stress from biochemical, physiological and pathological standpoints Provides the latest research on the development of improved therapy for a variety of lung diseases, including cancer Discusses various antioxidants that can be used in combating lung disease

Auteur
Prof. Sajal Chakraborti is a Professor of Biochemistry at the University of Kalyani, West Bengal, India. His research covers the role of proteases, oxidant and Ca2+ signalling in the pathogenesis of a variety of diseases. Prof. Chakraborti did is PhD from Calcutta University (1982) and DSc from Kalyani University (2014). He did post doctoral research at the Johns Hopkins University, University of Utah and New York Medical College. He received DBT-Senior Overseas Research Award for his research at the Brain Institute, University of Florida, Gainesville (1998-1999). He has been engaged in teaching and research in biochemistry for the past 40 years. He has published more than hundred original papers, 22 book chapters, 15 review articles and edited seven books published by Springer. Prof. Tapati Chakraborti is currently a Professor of Biochemistry in the Department of Biochemistry and Biophysics, University of Kalyani, West Bengal India. She did her PhD from CSIR-Indian Institute of Chemical Biology, Kolkata (1993). She did her post doctoral research at the Brian Institute, University of Florida, Gainesville, Florida, USA supported by Americal heart Association. Her post doctoral research mainly focused on beta-adrenergic receptor regulation in heart diseases. She is currently doing research on oxidant and calcium signalling- mediated pathogenesis of lung diseases and also parasitic diseases especially Leishmaniasis. She received several extramural research funding from CSIR, ICMR, DBT, DST, DAE and UGC (Govt. of India). She published more than 80 original research papers in different internationally reputed journals and 20 book chapters in different books published by Springer and Academic Press. She edited a book titled: Proteases in Human Diseases published by Springer in 2017.

Prof. Salil K Das is a Professor of Biochemistry and Cancer Biology at the Meharry Medical College, University of Tennesse, Nashville, TN, USA. He did ScD from the Massacussets Institute of technology in 1966 and DSc from the Calcutta University in1974. He published more than 150 original research papers in different International journal of repute. He also contributed 12 book chapters in different books of different international publishing company.

Prof. Dhrubajyoti Chattopadhyay is at present the Vice Chancellor, Amity University, Kolkata. He did his PhD from Bose Institute, Kolkata, India. He and did his post doctoral research at the Department of Cell Biology, Roche Institute of Molecular Biology, Nutley, New Jersey, USA (1985-1987); and also in the Department of Molecular Biology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA (1987-1988). He was the Dean and Pro-Vice Chancellor (Academic affairs) of Calcutta University. He did research on the role of oxidants in promoting different types of diseases. He published more than 100 original research paper and also published several chapters in different books published by different Internationally reputed publishing companies.

Contenu
Part A . General implications of oxidative stress on lungs.- Chapter 1. The nutrition in inflammatory lung diseases. Chapter 2. Oxidative Stress And Smoke Related Lung Diseases: A Tentative Approaches through blood, lungs and gut.- Chapter 3. Oxidative stress in neonatal lung diseases.- Chapter 4. DNA repair protein OGG1 in pulmonary infection and other inflammatory lung diseases.- Chapter 5. The dual role of oxidative stress in lung cancer.- Chapter 6. Cigarette smoke induced oxidative stress in type I and type II lung epithelial cells.- Chapter 7. Infectious lung diseases and Endogenous oxidative stress.- Chapter 8. Role of MMPs and Oxidants in Lung Diseases.- Chapter 9. Effect of exogenous chemical exposure-response relationship condensate oxidative stress in lung disease.- Part B . Inflammatory lung diseases.- Chapter 10. Oxidative stress and immune regulation during chronic respiratory diseases.- Chapter 11. Immunological basis of oxidative stress induced lung inflammation in asthma and COPD.- Chapter 12. Contribution of Aldose Reductase-Mediated Oxidative Stress Signaling in Inflammatory Lung Diseases.- Chapter 13. Oxidative Stress and Pulmonary Carcinogenesis through Mechanisms of Reactive Oxygen Species. How Respirable Particulate Matter, Fibrous Dusts and Ozone Cause Pulmonary Inflammation and Initiate Lung Carcinogenesis.- Part C . Other lung diseases.- Chapter 14. The Redoxomics of Bronchopulmonary Dysplasia.- Chapter 15. Oxidative stress in environmental lung diseases.- Chapter 16. Bronchopulmonary Dysplasia and Oxidative Stress in the Newborn.- Chapter 17. Pulmonary Oxidative Stress and Antioxidant Defence System in the Lung Aging, and Fibrotic and Diabetic Lungs.- Chapter 18. Mitochondrial alterations and oxidative stress in cystic fibrosis.- Part D . Degenerative lung diseases.- Chapter 19. Oxidative stress in chronic obstructive pulmonary disease.- Chapter 20. Oxidative stress induced autophagy-impairment and pathogenesis of chronic obstructive lung diseases.- Part E . Prevention and Therapeutics.- Chapter 21. Therapeutic targeting of oxidative stress and inflammation in Asthma and COPD and Pharmacological interventions with Phytochemicals.- Chapter 22. Diallyl trisulfide prospectively rescues Arsenic induced lung oxidative stress, inflammation through the activation of Nrf2/HO-1 signaling.- Chapter 23. Molecular therapeutic targets in tobacco-induced lung pathology.
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