Organozinc Derivatives and Transition Metal Catalysts

Auteur

Janine Cossy

is Professor of Organic Chemistry at the ESPCI Paris since 1990. Her research interests focus on the synthesis of natural products and/or biologically active compounds as well as on the development of synthetic methods.

Texte du rabat

Organozinc derivatives are now easy to prepare and their reactivity can be modified with transition metals. They are used in cross-coupling reactions with halides and pseudo-halides to form C-C bonds. The advantage of organozinc derivatives over Grignard reagents is that they are more chemoselective and have a higher funcional group tolerance. This book describes current aspects and limitations of the field, such as enantioselective couplings.