Omics Approaches, Technologies And Applications

This book is a concerted effort to put together the rapidly growing facets of biological data. It provides a platform for the readers to think about integrative approaches to solve complex biological problems. This fundamental book deals with the simplest concepts of omics to recent advancements in the field. The content is divided into seven chapters that provide insight into various omics approaches, omics technologies, and its applications. Each chapter delves into different molecular scales: genomics, transcriptomics, proteomics, and metabolomics. Further to provide a holistic view a chapter detailing microbiome has been included in the book. The sub-sections in the chapters is dedicated to introducing the various analytical tools such as next generation sequencing, chromatin immunoprecipitation, mass spectrometry, peptide mass fingerprinting, RNA Seq and NMR spectroscopy. It entails a chapter focused on the bioinformatics resources for analysis of the omics data. In summary, this comprehensive book emphasizes the recent advancements in the study of biomolecules spanning from DNA to metabolites.

The book comprehensively and coherently reviews the various aspects of omics including genomics, transcriptomics, proteomics, and metabolomics It skillfully intorduces the various omics tools including next generation sequencing, chromatin immunoprecipitation, mass spectrometry, peptide mass fingerprinting, RNA sequencing, and NMR spectroscopy It also focuses on the various bioinformatics which are utilized tools for the analysis of the omics data

Auteur

Dr. Preeti Arivaradarjan is Assistant Professor at Amity University, Noida, Uttar Pradesh, India. Previously, she had completed Ph.D. from School of Biological Sciences, Madurai Kamaraj University, Tamil Nadu, India. Her research inclination is towards the study of microbiome associated with pristine environments with a special interest for human oral microbiome. She has been conferred with various prestigious awards notably, Commonwealth Split-Site Doctoral Scholarship by Commonwealth Scholarship Commission in United Kingdom, Innovation in Scientific Pursuit for Inspired Research (INSPIRE) fellowship by Department of Science and Technology, Government of India, and gold medal for the best outgoing student of the year during master's program by Sri Ramachandra University, Chennai, India. Furthermore, she is a member of Indian Science Congress Association and is serving as a reviewer for numerous international journals. She has also published a number of research articles in the peer-reviewed international journals and has authored book chapters.

Dr. Gauri Misra is currently working as Assistant Professor at Amity University, Noida (U.P.), India. Before joining Amity University, she has worked as Assistant Professor at Hygia Institute of Pharmaceutical Education and Research, Lucknow (U.P.), India. From 2010 to 2011, she worked as a postdoctoral fellow at CHUL Research Centre, Quebec, Canada. As a postdoctoral fellow, she worked towards understanding the role of androgen receptor in the growth and proliferation of breast cancer cells using various structural biology approaches. During her doctoral studies at the Central Drug Research Institute, Lucknow (U.P.), India, she made an innovative contribution towards understanding the structural and functional characterization of the Plasmodium falciparum proteins that are involved in the transit peptide-mediated pathway. Her research interests is in the field of pathogen biology and cancer.She is striving through her research efforts in the field of structure based drug design for a better future. She is the recipient of many awards including the Young Scientist best scientific presentation award at International Conference on "Trends in Biochemical and Biomedical Research", Banaras Hindu University, Banaras, India in 2018, prestigious Eli-Lilly Asia Outstanding Thesis Award (first prize) in 2009 and best oral presentation award at the "National Seminar on Crystallography-37," held in Jadavpur University, Kolkata in 2008. She has been an outstanding performer receiving gold medals and honors at various stages of her academic journey. Previously, she was selected as visiting Scientist under the INSA bilateral exchange program to visit the Israel Structural Proteomics Center situated at Weizmann Institute of Science, Rehovot, Israel, in 2014.

She is serving as the reviewer for various renowned international journals. Furthermore, she is a member of many scientific societies including the Indian Biophysical Society, Indian Science Congress Association and Indian Crystallographic Association. Till date, she has authored and co-authored 13 articles in the various peer-reviewed journals. She has successfully edited a book on Biophysics with Springer in 2017. During the past 8 years, she has been actively involved in both research and teaching graduate and postgraduate students.

Contenu
Module 1 Introduction to omics.- Module 2 _Genomics.- Module 3 _Transcriptomics.- Module 4 Proteomics.- Module 5 Metabolomics.- Module 6 _Microbiome.- Module 7 Bioinformatics resources.