Nutrition in the Control of Inflammation

Auteur
Bradley S. Ferguson is an Associate Professor of Nutrition at the University of Nevada, Reno, Nevada. His lab adopts integrative, translational research approaches that encompass bioinformatics, in vitro cell culture, and in vivo animal models to elucidate dietary food components that act as epigenetic modifiers, as well as the role of dietary epigenetic modifiers on pathological cardiac signaling, gene expression, and remodeling. He also seeks to understand how sarcomere protein acetylation links metabolic disease (obesity and diabetes) to pathological cardiac remodeling and skeletal muscle dysfunction. Dr. Ferguson has published his findings across a wide range of peer-reviewed journals, including Scientific Reports, Journal of Animal Science, American Journal of Physiology, Cell Reports, PNAS, and *the *Journal of Molecular and Cellular Cardiology. Steven Frese is an Assistant Professor of Nutrition at the University of Nevada, Reno, Nevada and holds an appointment as an Adjunct Assistant Professor at the Department of Food Science and Technology at the University of Nebraska, Lincoln. His research applies principles of microbial ecology and evolutionary biology to develop rational interventions to improve human health via the gut microbiome. This includes applying advanced techniques including bioinformatics, DNA/RNA sequencing, and mass spectrometry to determine strain- and ecosystem-level interactions both in vitro and in human clinical trials. His work has primarily focused on the gut microbiome in early life, and the role of diet and the microbiome in shaping infant health and development. Dr. Frese's work has been published in a variety of broad interest peer-reviewed journals including Cell, Science Translational Medicine, Cell Host & Microbe, and PLoS Genetics, as well as audience-specific journals including Pediatric Research, Glycobiology, and Bioinformatics.

Texte du rabat

Nutrition in the Control of Inflammation: Emerging Roles for the Microbiome and Epigenome offers a comprehensive overview on how our diet promotes or attenuates inflammation to regulate inflammatory diseases. Broken into five sections, this book presents an introduction to the microbiome and epigenome in nutrition, subsequently covering diet, lifestyle, and the microbiome in the development of inflammatory diseases, nutrition and the epigenome in metabolic and cardiovascular diseases, diet, epigenetics, and microbiome. This book also addresses health-disparities in diet, epigenetics, and gut microbes. It will be of interest to nutrition researchers, nutritionists, and postgraduate students, as well as others working in, studying, and researching related fields.

Contenu

Section I. Introduction1. Introduction: Nutrition, the microbiome, and the epigenome in human health and disease Section II. Diet, lifestyle and the microbiome in development and inflammatory diseases2. The microbiome across the lifecycle3. The microbiome in infant gut health and development4. The microbiome in early life as a risk factor for autoimmune diseases5. The microbiome in gut inflammation and carcinogenesis6. Obesity and the microbiome: A role for microbes in insulin resistance7. Fiber and the gut microbiome and its impact on inflammation8. Diet-specific impacts on the gut microbiome and their relation to health and inflammation9. Hypertension, Obesity, and the microbiome in cardiovascular disease10. Bariatric surgery, gut microbes, and metabolic health11. Caloric restriction in the microbial regulation of inflammaging12. Exercise, the gut microbiome and inflammatory disease Section III. Nutrition and the epigenome in metabolic and cardiovascular diseases13. Obesity, histone acetylation and insulin resistance14. Obesity, DNA methylation and metabolic disease15. Diet, histone modifications and cardiovascular diseases16. Diet, DNA methylation and cardiovascular diseases17. Obesity and non-coding RNAs in epigenetic inheritance of metabolic disease18. Caloric restriction in the epigenetic regulation of aging and longevity19. Exercise in epigenetic programing throughout life Section IV. Diet, epigenetics, and the microbiome in inflammatory disease20. Gut microbiome, epigenetics and neuro-inflammatory disease21. Caloric restriction, gut microbes, epigenetics and inflammaging22. Obesity, gut bacteria and the epigenetic control of metabolic disease23. The microbiome-epigenome axis in infant gut health and development24. The microbiome and epigenome intersect to regulate gut inflammation Section V. Conclusions: Health-disparities in diet, epigenetics and gut microbes25. Race, gender and ethnicity in the control of our gut microbes26. The role for social-environmental influences in epigenetic determination27. Practical applications for diet and lifestyle to improve microbial and epigenetic health