Neural Transplantation and Regeneration

With contributions by numerous experts

Four years ago the first international symposium dealing with neural transplan tation was organized as a satellite conference to the annual meeting of the Society for Neuroscience in Los Angeles, California. The expanded proceed ings of that symposium were published by Springer-Verlag in 1983 in a volume entitled Neural Tissue Transplantation Research. We were sufficiently pleased with the results of that effort to organize a second satellite international sympo sium on Neural Transplantation and Regeneration in conjunction with the 13th Annual Meeting of the Society for Neuroscience in Boston in the fall of 1983. Paralleling the growing body of research dealing with various aspects of neural transplantation, the scope of this second symposium was broadened to include not only transplantation but also regeneration. Additionally, topics of clinical interest were addressed as well as issues of basic research. The promise apparent in that first conference is still seen in the second as more and more investigators apply their talents in an attempt to understand this infant field of research. The present volume represents an expanded version of the material presented at the second symposium. We wish to thank all of the contributors to the conference and to this volume for their insight and their assistance.

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With contributions by numerous experts

Contenu

1 Neural Transplantation in Spinal Cord under Different Conditions of Lesions and Their Functional Significance.- 2 Unequivocal Regeneration of Rat Optic Nerve Axons into Sciati Nerve Isografts.- 3 The Differentiation of Non-Neuronal Elements in Neocortical Transplants.- 4 Uses of Neuronal Transplantation in Models of Neurodegenerative Diseases.- 5 Differentiation of Rat Fetal Retina Transplanted to the Occipital Cortex either in Isolation or Together with a Second Transplant of Superior Colliculus to Induce Sprouting of Optic Fibers.- 6 Qualitative Studies of Reactive Events in the Site of Injury Following Transection of the Spinal Cord in the Rat.- 7 Regenerative Growth of Retinofugal Axons into and through Neocortical Transplants Following Transection of the Optic Tract in Adult Rats.- 8 The Role of Neuroglia in Axonal Growth and Regeneration.- 9 The Role of Schwann Cells in the Repair of Glial Cell Deficits in the Spinal Cord.- 10 The Motoneuron and Its Microenvironment Responding to Axotomy.- 11 Cellular Interactions between Transplanted Autonomic Ganglia and the Developing Brain.- 12 A Behavioral and Histological Examination of Young Rats Receiving Homotopic Embryonic Neural Transplants in Motor Cortex.