Nanoparticles for Drug Delivery

This book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.

Discusses the nanoparticle preparations under current investigation for drug delivery applications Discusses toxicity and potential hazards with respect to nanoparticle formulations Discusses identification of promising candidates with optimal pharmacokinetics and clearance from the body

Auteur

K. S. Joshy is a post-doctoral researcher at the International and Inter University Center for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kerala, India. His research interests include synthesis and charecterization of nanoparticles with application for drug delivery. He has authored 10 research articles in high-impact journals, 1 book chapter and has been a co-editor on 1 book. Sabu Thomas is currently Professor and Pro-Vice Chancellor in Mahatma Gandhi University, Kerala, India, in addition to being the founder director of the International and Inter University Centre for Nanoscience and Nanotechnology. After his B.Tech in polymer science and rubber technology from University of Cochin, he went on to do his PhD from Indian Institute of Technology, Kharagpur. Prof Thomas is the Chief Editor of Nano-Structures & Nano-Objects and has received many national and international awards, including Fellowship of the Royal Society of Chemistry, MRSI award, SESR award, the Dr APJ Abdul Kalam Award for Scientific Excellence, an honorary degree by Université de Lorraine, and multiple fellowships by prestigious societies and universities. Prof Thomas' research has spanned many areas of nanocomposite and polymer science and engineering, and he has edited more than 70 books, holds 5 patents and has authored over 750 research publications. Dr Vijay Kumar Thakur is currently a faculty member in the School of Aerospace, Transport and Manufacturing at Cranfield University. Prior to this, Dr. Thakur worked as a Staff Scientist in the School of Mechanical and Materials Engineering at Washington State University, U.S.. Some of his other prior significant appointments include being a Research Scientist in Temasek Laboratories at Nanyang Technological University, Singapore and a Visiting Research Fellow in the Department of Chemical and Materials Engineering at LHU Taiwan. He did his post-doctoral study in Materials Science & Engineering at Iowa State University and received Ph.D. in Polymer Chemistry (2009). He received his B.Sc. (Chemistry, Physics & Mathematics), B.Ed. and M.Sc. degree in Organic Chemistry from Himachal Pradesh University, Shimla, India. Dr. Thakur is an editorial board member of several SCI peer reviewed international journals as well as member of scientific bodies around the globe.

Contenu
Chapter 1: Nanotechnology and its implication in drug delivery.- Chapter 2: Solid lipid nanoparticles in drug delivery.- Chapter 3: Hydrogel nanoparticles, Nanocrystals & Nanosuspensions for drug delivery.- Chapter 4: Biomimetic nanoparticles in drug delivery.- Chapter 5: Quantum dots in drug delivery.- Chapter 6: Stimuli ressposive hybrid polymeric nanoparticles for targeted drug delivery.- Chapter 8: Ceramic based hybrid nanoparticles in drug delivery.- Chapter 9: Application of hybrid NPs in image guided drug delivery.- Chapter 10: Biological understanding of nanoparticulate drug delivery.- Chapter 11: Challenges in nanoparticle designing for drug delivery.- Chapter 12: Biomaterials for anti-cancer drugs.- Chapter 13: Biomaterials for anti-viral drug delivery.- Chapter 14: Biomaterials for anti bacterial drug delivery.- Chapter 15: Theoretical modelling of drug delivery.