NanoBioMedicine

This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

This book presents an updated account of the several state-of-the art-examples of the application of Nanotechnology in the field of biomedical research The book provides an unparalleled reservoir of information about Nanotoxicology It also discusses the future prospects of targeting cancer stem cells through nanotherapeutic approaches for cancer treatment It provides an updated account of development of the virus-based nanoparticle system as vaccine therapy for the prevention and treatment of various infectious diseases

Auteur
Prof. (Dr.) Shailendra K. Saxena is a Vice Dean and Professor at King George's Medical University, Lucknow. His primary research interest is to understand the molecular mechanisms of host defense during human viral infections and to develop predictive, preventive and therapeutic strategies against these diseases. Prof. Saxena's work has been published in various high impact factor reputed international journals. He has been honored by several prestigious National and International Awards, Fellowships and Scholarships in India and abroad, including Young Scientist Awards, BBSRC India Partnering Award and named as the Global Leader in Science by The Scientist magazine (USA) and International Opinion Leader/Expert that are involved in the vaccination for JE by IPIC (UK). He has been elected Fellow of The Royal Society of Biology UK (FRSB), The Royal Society of Chemistry UK (FRSC), The Academy of Environmental Biology, India (FAEB), Indian Virological Society (FIVS), The Biotech Research Society, India (FBRS); and Fellowship of the (European) Academy of Translational Medicine Professionals, Austria (FacadTM). He has been awarded Dr. JC Bose National Award of Department of Biotechnology (DBT, Min. of Science & Technology, Govt. of India) in Biotechnology and has an active collaboration with various US universities.

Prof. (Dr.) S. M. Paul Khurana, Ph.D. (1969); PD Research in Adv Virology at Kyushu University, Japan, University of Minnesota, USA with specialization in Immunodiagnostics. He is currently Professor of Biotechnology and Head, Univ Science Instrument Centre. Amity University, Gurgaon, Haryana. Earlier he has served as the Vice-Chancellor, Rani Durgavati University, Jabalpur 2004-2009, Director at Central Potato Research Institute, Shimla 2002-2004, the Founder Director, Amity Inst. of Biotechnology, at Gurgaon Haryana from 2010-2016, Dean Faculty of Science, Engineering & Tech 2013-2016; Consultant CIP/FAO, 1992, 1996,1997. He has 53 years of research experience in Pathology Virology, Biotechnology on plant viruses. He has pioneered the use of ELISA and ISEM for the potato viruses. Till now, he has published more than 230 research papers in reputed international journals, 105 reviews/chapters, edited 16 books and guided 16 PhDs. He had been honored with more than 30 Awards/Honors to his credit including, Mundkur Memorial Award/Gold Medal, 1992; CPRI Golden Jubilee Outstanding Achievement award, 2000; NatlEnvSciAcad Best Sci of the Year, Award 2002; CPRI S Ramanujam Memorial Award, 2003;Ch. Devi Lal outstanding AICRP Award, 2005; UNO-Dr S Radhakrishnan Int'l Award for Excellence in Higher Education Management, 2006; ICAR Team Research Award, 2010, ISCA-Platinum Jubilee (lecture) Award, 2010; SAARC Outstanding Achievement Award, 2011, ISMPP Lifetime Achievement Award, 2012; HSI-Shivshakthi Lifetime Achievement Award, 2013; Eminent Scientist Honor: ISCA Sir JC Bose Medal, 2013; CHAI-Lifetime Achievement Award, 2016 and ISMPP Prof YL Nene Outstanding Teacher of Plant Pathology, 2017, Fellow National Acad of Agric Sciences, National Academy of Biological Sciences. He was deputed for International Conferences, by the GOI/ICAR/UGC in UK, Europe, USA, Canada, Japan, Peru, Africa, etc. Convened Global Potato Confr, N Delhi , 1999.

Résumé

Contenu

Chapter 1 .Current Advances in Nanotechnology and Medicine.- Chapter 2. Least Explored Small Wonders: Nano-biotechnology.- Chapter 3. Modern Approaches in Nanomedicine for neuroAIDS and CNS drug delivery.- Chapter 4. Nanobiotechnology: Paving the way to personalized medicine.- Chapter 5 . Nanomedicine in cancer stem cell therapy.- Chapter 6. Nanobiosensor: Current Trends and Applications.- Chapter 7. Transition Metal Oxide Nanoparticles: A New Horizon in Cancer Treatment.- Chapter 8. Nanomedicine meets microRNA expression and function in prostate cancer.- Chapter 9. Biomedical applications of Viral Nanoparticles in vaccine therapy.- Chapter 10. HIV: Biology to Nanomedicine.- Chapter 11. Current Advances in Phage Inspired Nanocarriers Based Therapy.- Chapter 12. Nanophytotherapeutic potential of Essential Oils against Candida infections.- Chapter 13. Molecular tests for the Diagnosisof Tuberculosis: Nanodiagnostics Approaches.- Chapter 14. Molecular Mechanisms of drug resistance in Mycobacterium tuberculosis: Role of nanoparticles against Multi-Drug Resistant tuberculosis (MDR-TB).- Chapter 15. Nano-Mass spectrometry (nano-MS) based lipidomics.- Chapter 16. Techniques to understand Mycobacterial Lipids and use of Lipid Based Nanoformulations for Tuberculosis Management.- Chapter 17. Recent trends and challenges in Patches for cardiac tissue reengineering: role of Nanomaterials.- Chapter 18. Cyclic dinucleotides: Big roles of small molecules and its role in nanotechnology and medicine.- Chapter 19. Antibodies: Biology to Therapeutics and its role in nanomedicine.- Chapter 20. Nanotoxicology in Medicine.- Chapter 21. Antibody-targeted nanoparticles for cancer treatment.- Chapter 22. Nanoparticle mediated combined photothermal and photodynamic therapy.- Chapter 23. Nanotechnology based devices and its applications in medicine- Chapter 24. Opportunities in clinical translation and commercialization of nanomedicine.

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