Molecularly Imprinted Polymers: Path to Artificial Antibodies

The book delves into the intricate realm of Molecularly Imprinting Polymers (MIPs) functioning as artificial antibodies. The book explores several subjects, such as the basic principles, historical development, methods for creating and analyzing MIPs, creation of specific recognition sites, computational modeling, responsive behavior to stimuli, and the nano-scale applications of MIPs. Furthermore, it emphasizes the pivotal role of MIPs in the detection of cancer, infectious diseases, and the detection of bacteria and viruses. In addition, the book explores the field of different sensor technologies, specifically focusing on MIP-based electrochemical and optical sensors. It also highlights how these sensors might be integrated into wearable, flexible, and chip sensors. In addition, the book explores developing technologies and potential future applications of MIPs as artificial antibodies. This book offers a complete grasp of the promise and limitations of MIPs by providing insights into their challenges and real-time applications.

The book will be a useful resource for researchers, students, professionals, and practitioners in bioengineering, biotechnology, medicine, and ethics.

Covers basic concepts, techniques, nano applications, and emerging technologies in artificial antibodies Explores MIPs' significance in cancer detection, infectious disease monitoring, personalized medicine, and more Bridges the gap in theory and applications of MIPs

Auteur

Dr. Santanu Patra is working in the field of materials chemistry, specializing in the integration of functional materials with macro-, micro- nano-system stems and their multifaceted applications. He received his PhD in chemistry from the Indian Institute of Technology (ISM) in Dhanbad, India, where he gained expertise in cutting-edge technologies related to molecularly imprinted nanotechnology and electrochemistry. He then worked as a group leader/researcher in two R & D companies and at Khon Kaen University, Thailand. Currently, Dr. Patra is associated with the Technical University of Denmark, where he is continuing his research on multifaced nanotechnological approaches towards biomedical applications. Through his research, Dr. Patra aims to develop advanced and innovative technologies that can address some of the most pressing challenges for sustainable development. He has authored or co-authored more than 60 research/review articles and book chapters along with two patents. Dr. Patra serves as an editor/editorial board member of several international peer-reviewed journals and has edited several important books.

Dr. Sudheesh K. Shukla works in the area of translational research and development of bioelectronics devices for disease alert and disorder with a major focus on interfacing chemistry (material science) and engineering for better healthcare (biology) and environmental applications. Currently, Dr. Shukla's research involves real-sample analysis of biochemical markers for personalized healthcare monitoring. In particular, Dr. Shukla is interested in integrating biomaterials with micro- and nanosystems for sensing and actuation technologies. Dr. Shukla is the author of numerous articles in peer-reviewed journals and as well a prolific author and editor of several scientific monographs in healthcare and environmental disciplines in several publications. Dr. Shukla serves as an editor/editorial board member of several international peer-reviewed journals like Chemosensor, Sensor International, Coronavirus, Reports in Electrochemistry, Chemistry Africa, Topic in Catalysis and Chemical Physics Impact, etc.

Prof. Mika Sillanpää received his M.Sc. (Eng.) and D. Sc. (Eng.) degrees from Aalto University where he also completed an MBA degree in 2013. Since 2000, he has been a full professor/adjunct professor at the University of Oulu, the University of Eastern Finland, the LUT University, the University of Eastern Finland, and the University of Johannesburg. He has supervised over 60 PhDs and has been a reviewer in over 250 academic journals. Mika Sillanpää has published more than 1000 articles in peer-reviewed international journals. He has served on the editorial boards of several scholarly publications. Having an h-index of 129, his publications have been cited over 80000 times (Google Scholar). Mika Sillanpää has received numerous awards for research and innovation. He also received a Literature award from the Water Association of Finland in 2018. In 2019, 2020, and 2021, he was listed as a highly cited researcher by Thomson Reuters in two different disciplines, among approximately 200 other top researchers (covering all fields of science). He was listed as one of the World's Top 2% Scientists by Stanford University. In 2022, he was awarded the Provincial Innovative Talent of Zhejiang Province, China.

Contenu

Chapter 1. Overview of MIPs as Artificial Antibodies: Fundamental and various applications.- Chapter 2. Synthesis and Characterization of MIPs.- Chapter 3. MIP-based Electrochemical Sensors.- Chapter 4. MIP-based Electrochemical Sensors in The Detection of Opioids, Benzodiazepines and Psychoactive Compounds.- Chapter 5. Molecularly Imprinted Polymers Based Electrochemical Sensors.- Chapter 6. Molecularly Imprinted Polymer-Based Electrochemical (MIP-EC) Sensors for Biomarker Detection and Quantification.- Chapter 7. Harnessing Molecularly Imprinted Polymers as Artificial Antibodies in Electrochemical Sensors for Disease Detection and Monitoring.- Chapter 8. Advancements in Molecularly Imprinted Polymer-based Electrochemical Sensors: Fabrication, Functionalization, Applications and Future Perspectives.- Chapter 9. MIP-based Optical Sensors: Exploring Principles and Applications as Artificial Antibodies in Disease Detection and Monitoring.- Chapter 10. Molecularly Imprinted Polymers in Optical Sensors: Principles, Fabrication and Applications for Disease Detection and Monitoring.- Chapter 11. MIP Based Chip Sensors.- Chapter 12. Importance of MIPs as artificial antibodies for the detection of bacteria and viruses.- Chapter 13. Important of MIPs as artificial antibodies in cancer detection and monitoring.- Chapter 14. Advancements in Molecularly Imprinted Polymers for Selective Recognition of Cancer Biomarkers.- Chapter 15. Importance of Molecularly Imprinted Polymers as Artificial Antibodies in Drug Delivery and Tissue Engineering.- Chapter 16. Importance of MIPs as Artificial Antibodies in Drug Delivery and Tissue Engineering.- Chapter 17. Aspects of molecularly imprinted polymers as synthetic antibodies for revelation and surveillance of Cancer.