miRNAs, Human Health and Diseases

This new volume of the book series Epigenetics and Human Health is dedicated to microRNAs (miRNAS), regulatory non-coding RNAs that have important roles in the control of gene expression both at posttranscriptional and transcriptional levels.

Endogenous miRNAs regulate gene expression patterns in a sequence-specific manner. These short sequences may serve as potential therapeutic targets in the treatment of complex diseases including cancer, cardiovascular diseases, neurocognitive disorders, respiratory diseases and pathogenic infections. Moreover, miRNAs hold promise to be used as extensive diagnostic and prognostic markers of disease.

miRNAs, Human Health and Disease is an essential reading for graduate and undergraduate students, researchers, and academics interested in the latest developments on non-coding RNA-mediated pathways associated with health and disease.

Explains miRNA-mediated pathways associated with health and disease states Offers an overview on the regulatory role of miRNAs Summarizes latest updates on the use of miRNAs as therapeutic agents and biomarkers

Auteur

Luis María Vaschetto obtained his Ph.D. in Biological Sciences from the Universidad Nacional de Córdoba (Argentina). He was a postdoctoral researcher at the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) and a Research Associate at the South Dakota State University (SDSU). He has been the first author of more than 10 academic articles and also published several book chapters. His research mainly focuses on understanding the epigenetic mechanisms involved in plant and animal development, as well as their effects on human health and diseases.

Texte du rabat

This new volume of the book series Epigenetics and Human Health is dedicated to microRNAs (miRNAS), regulatory non-coding RNAs that have important roles in the control of gene expression both at posttranscriptional and transcriptional levels.

Endogenous miRNAs regulate gene expression patterns in a sequence-specific manner. These short sequences may serve as potential therapeutic targets in the treatment of complex diseases including cancer, cardiovascular diseases, neurocognitive disorders, respiratory diseases and pathogenic infections. Moreover, miRNAs hold promise to be used as extensive diagnostic and prognostic markers of disease.

miRNAs, Human Health and Disease is an essential reading for graduate and undergraduate students, researchers, and academics interested in the latest developments on non-coding RNA-mediated pathways associated with health and disease.

Contenu

Chapter 1. MiRNomics: An Introduction to MicroRNA Biology.- Chapter 2. MicroRNA Databases.- Chapter 3. Bioinformatics Tools to Study the Role of miRNAs.- MicroRNAs as Promising Therapeutic Targets.- Chapter 4. MicroRNAs as Promising Therapeutic Targets.- Chapter 5. The Interplay Between MicroRNAs and Genetic Diseases.- Chapter 6. Circulating miRNAs as Biomarkers for Early Disease Diagnosis.- Chapter 7. miRNAs as Biomarkers for Neurodegenerative Diseases.- Chapter 8. MicroRNAs and Immune-Related Disorders.- Chapter 9. MicroRNAs and Cardiovascular Diseases.- Chapter 10. miRNAs in Aging.- Chapter 11. MicroRNAs in Viral Infection.- Chapter 12. Inter-Kingdom Signalling: Exploring the Relationships among Microorganisms and microRNAs in Human Health.