Mathematical Modelling of Biosystems

Gives an overview of mathematical and computational modelling of biosystems including biological phenomena in general Includes supplementary material: sn.pub/extras

Texte du rabat

This volume is an interdisciplinary book, which introduces, in a very readable way, state of the art research in the fundamental topics of mathematical modelling of Biosystems. These topics include: the study of Biological Growth and its mechanisms, the coupling of pattern to form via theorems of Differential Geometry, the human immunodeficiency virus dynamics, the inverse folding problem and the possibility of analysing true protein backbone flexibility, the Biclustering techniques for the organization of microarray data, the analytical approach to the modelling of biomolecular structure via Steiner trees, the action of biocides on resistance mechanisms of mutated and phenotypic bacteria strains, a description of the fundamental processes for the distribution and abundances of species towards a unified theory of Ecology, and a special introduction to Protein Physics aiming to explain the all-or-none first order phase transitions from native to denatured states.

Résumé
This volume is an interdisciplinary book which introduces, in a very readable way, state-of-the-art research in the fundamental topics of mathematical modelling of Biosystems. In short, the book offers an overview of mathematical and computational modelling of biosystems including biological phenomena in general. There is also a special introduction to Protein Physics which aims to explain the all-or-none first order phase transitions from native to denatured states.

Contenu
Elastic Growth Models.- A Model of Pattern Coupled to Form in Metazoans.- Mathematical Modeling of HIV-1 Infection and Drug Therapy.- Overcoming the Key Challenges in De Novo Protein Design: Enhancing Computational Efficiency and Incorporating True Backbone Flexibility.- The Improved Heuristic for Consistent Biclustering Problems.- The Steiner Tree Problem and Its Application to the Modelling of Biomolecular Structures.- Phenotypic Switching and Mutation in the Presence of a Biocide: No Replication of Phenotypic Variant.- From Spatial Pattern in the Distribution and Abundance of Species to a Unified Theory of Ecology: The Role of Maximum Entropy Methods.- Protein Structure and Its Folding Rate.