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This volume covers current research in the usage of magnetic nanoparticles for drug delivery. It discusses synthesis methods, stabilizers used for surface coating on MNPs, and potential target ligands which can be used to ferry payloads to the targeted disease region. It also highlights the factors affecting delivery efficiency and toxicity, as well as the different routes of administration. The content also focus on the use of these carriers for gene therapy and to target brain tumors. This volume will be of interest to researchers working on drug discovery and delivery platforms.
Covers the use of magnetic nanoparticles in image guided drug delivery Discusses biocompatibility of magnetic nanoparticles Focuses on the parameters influencing drug delivery efficiency
Auteur
K. S. Joshy is a post-doctoral researcher at the International and Inter University Center for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kerala, India. His research interests include synthesis and charecterization of nanoparticles with application for drug delivery. He has authored 10 research articles in high-impact journals, 1 book chapter and has been a co-editor on 1 book.
Sabu Thomas is currently Professor and Pro-Vice Chancellor in Mahatma Gandhi University, Kerala, India, in addition to being the founder director of the International and Inter University Centre for Nanoscience and Nanotechnology. After his B.Tech in polymer science and rubber technology from University of Cochin, he went on to do his PhD from Indian Institute of Technology, Kharagpur. Prof Thomas is the Chief Editor of Nano-Structures & Nano-Objects and has received many national and international awards, including Fellowship of the Royal Society of Chemistry, MRSI award, SESR award, the Dr APJ Abdul Kalam Award for Scientific Excellence, an honorary degree by Université de Lorraine, and multiple fellowships by prestigious societies and universities. Prof Thomas' research has spanned many areas of nanocomposite and polymer science and engineering, and he has edited more than 70 books, holds 5 patents and has authored over 750 research publications.
Dr Vijay Kumar Thakur is currently a faculty member in the School of Aerospace, Transport and Manufacturing at Cranfield University. Prior to this, Dr. Thakur worked as a Staff Scientist in the School of Mechanical and Materials Engineering at Washington State University, U.S.. Some of his other prior significant appointments include being a Research Scientist in Temasek Laboratories at Nanyang Technological University, Singapore and a Visiting Research Fellow in the Department of Chemical and Materials Engineering at LHU-Taiwan.He did his post-doctoral study in Materials Science & Engineering at Iowa State University and received Ph.D. in Polymer Chemistry (2009). He received his B.Sc. (Chemistry, Physics & Mathematics), B.Ed. and M.Sc. degree in Organic Chemistry from Himachal Pradesh University, Shimla, India. Dr. Thakur is an editorial board member of several SCI peer reviewed international journals as well as member of scientific bodies around the globe.
Contenu
Chapter 1: Surface chemistry and properties of magnetic nanoparticles.- Chapter 2: Magnetic nanoparticles for cancer treatment.- Chapter 4: Magnetic nanoparticles for image guided drug delivery.- Chapter 5: Tailoring of magnetic nanoparticles for biomedical applications: Chapter 6: Coating of magnetic nanoparticles an in depth understanding of property changes.- Chapter 7: Biocompatibility and surface functionalisation of magnetic nanoparticles for drug delivery.- Chapter 8: Superparamagnetic nanoparticles in cancer treatment.- Chapter 9: Parameters influencing drug delivery efficiency of magnetic nanoparticles.- Chapter 10: Multifunctional magnetic nanoparticles as smart drug delivery systems.- Chapter 11: Magnetic nanoparticles for the diagnosis and therapy of brain tumors.- Chapter 12: Magnetic nanoparticles for gene delivery.- Chapter 13: Understanding of different magneticnano drug carriers.- Chapter 14: Routes of administration of magnetic nanoparticles.- Chapter 15: The fate of magnetic nanoparticles.