Locoregional Tumor Therapy

This book reports on locoregional tumor therapies including optimized chemotherapy and chemoembolization for hepatocellular carcinoma, stereotactic radiosurgery, radiofrequency ablation, chemoembolization of liver metastases using drug-eluting beads and more.

This book presents, in condensed form, the clinical results achieved by means of various locoregional tumor therapies employed for different indications. In so doing, it will allow the reader to rapidly retrieve the information on indications and effectiveness that is required for optimal integration of these highly effective therapies into modern, complex treatment strategies.

The renaissance in locoregional tumor therapies is an ongoing process. New chemotherapeutic schedules, especially for liver and lung tumors, have been developed during the past few years. Other targeted therapies, such as radioembolization, microwave ablation, and HIFU techniques, and new pharmaceuticals for intra-arterial therapy have been developed and implemented in clinical practice. Furthermore, the advantages of unlimited combination of starch microspheres with various antitumor agents, supported by effective ischemia, have been increasingly exploited. The second edition of this book reflects these advances and includes entirely new chapters on the role of intraperitoneal perfusion in treating peritoneal carcinomatosis and the use of limb perfusion. Locoregional Tumor Therapy will be invaluable for all practitioners who work with cancer patients.

Presents up-to-date information on the clinical results achieved by locoregional tumor therapies Aids optimal integration of these therapies into modern, complex treatment strategies Fully reflects advances since the first edition Includes new chapters on intraperitoneal and limb perfusion

Auteur
Thomas Vogl , MD, PhD is a Professor of Radiology and Head of the Department of Diagnostic and Interventional Radiology at Frankfurt University Hospital in Germany where he is also appointed Chairman of the Frankfurt Klinikallianz. Prof. Vogl graduated from Ludwig-Maximilian University of Munich with a doctorate degree. In 1988 he obtained the degree of Assistant Professor at the University of Munich, in 1992 Associate and Full Professor of the Free University of Berlin, and in 1995 Professor of the Humboldt University Berlin. From 1991-1997 he worked as Senior Faculty Diagnostic Radiologist at the Virchow Clinics in Berlin. He has been Head of the Department of Diagnostic and Interventional Radiology at the University of Frankfurt for 18 years. Prof. Vogl is recipient of several honorary awards and a member of multiple national and international radiological and oncological societes and editorial board of journals. Prof. Vogl is the author/co-author of more than 150 peer-reviewed publications and numerous chapters and review articles focused on oncology and oncologic imaging. He serves as a reviewer for multiple radiological and clinical oncological publications.
Alberto Sobrero, MD, is the head of the Medical Oncology Unit at Ospedale San Martino in Genova, Italy. After his MD at the University of Genova, he took up the position of Postdoctoral Associate in Medical Oncology at Yale University, Connecticut. Before returning to Genova in 1985, he completed a residency in Internal Medicine at the Yale Affiliated Norwalk Hospital. From 2002 to 2006, Professor Sobrero was the chairman of the EORTC Protocol Review Committee and was a member of the of the ASCO-FECS Clinical Research faculty at Flims for 7 years. He served on the editorial board of the Journal of Clinical Oncology 2004-2006 , was part of the ASCO Scientific Committee (2007-2008) and the ESMO Educational Committee (2008-2014), chair of the GI Committee (2012-2016) and president of the ESMO Nominating Committee. He received the ESMO award in 2016. His main research interests include gastrointestinal cancer treatment and design and interpretation of clinical oncology trials.
Franco Orsi, MD , is the Chief of the clinical Division of Interventional Radiology at the European Institute of Oncology in Milan, Italy. After graduation, he completed the school of Radiology at the University of Rome La Sapienza, directed by Prof. Plinio Rossi. In 1992 he attended the Interventional Radiology Department and the Robert Steiner MR Centre at the Institute of Radiology of the Hammersmith Hospital of London (Royal Postgraduate Medical School), directed by Prof. D.J. Allison. In 1994 he attended the Radiologic Pathology Course at AFIP (Armed Force Institute of Pathology) of the Walter Reed Hospital on Washington DC, USA. From 1994 as Tutor and from 1999 as Professor at the Residency School of Radiation Therapy at the University La Statale in Milan. Active Fellow of the European Society of Interventional Radiology, founded the Italian-European Society of Interventional Radiology in 2014. Is author and co-author of more than 100 peer-reviewed publications and chapters focused on interventional radiology and interventional oncology.

About the author -texts for Van Cutsem to follow.

Contenu
Part 1: Basics of Regional Tumor therapies: Pharmacokinetic of Locoregional Tumor Therapies.- Embolization Materials, Catheter, IA-port systems.- Part 2: Intra-arterial Therapies: Liver: HCC.- Liver Metastases of CRC- Liver Metastases of Neuroendocrine Tumors and CCC.- Liver metastases of other indications.- Part 3: Intra-arterial Therapies: Lung, Head and Neck: Lung.- Head and Neck.- Part 4: Thermoablation: Liver.- Lung.- Part 5: Other locoregional Tumor Therapies: Treatment of Peritoneal Carcinomatosis.- Limb Perfusion.