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This volume contains the contributions to a symposium held at Gatlinburg, Tennessee, under the auspices of the Oak Ridge National Laboratory, in April, 1971. In the past, these proceedings had appeared as a supplement to the Journal of Cellular Physiology. Due to the nature of the subject ma terial and the relevance of the topic of the symposium to the readers of BIOMEMBRANES, it was agreed by the organizers of the symposium to publish the contributions of the partici pants as a separate volume in BIOMEMBRANES. It had been originally envisaged that, from time to time, the proceedings of a conference whose subject matter was directly related to the scope of this series would be included. The proceedings are being published exactly as they have been submitted to the Editor without the usual editorial re V1S10n. This is being done to increase the speed of publica tion. For the same rOeason, no indices have been provided since the time needed to prepare an adequate subject index would have unnecessarily delayed publication. Included in the proceedings are short reports of a number of workshops that were held during the conference. The editor has received excellent cooperation from both the organizers of the conference and the several contributors to this volume. If the experiment is a success, it is thanks to their promptness.
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Membranes and the Coordination of Cellular Activities.- Relations of Membrane Functions and Ultrastructure.- Biochemistry of Bacterial Membranes: The Complex Lipids.- Biochemical and Genetic Studies on Sugar Transport in Bacteria.- The Use of Thermosensitive Mutants of E. coli in the Analysis of Cell Division.- Cytochemical Staining Reactions for Enzymes in Cytoplasmic Organelles.- Microscopic Properties of Discrete Membrane Loci.- Comparison of Cellular Membranes of Liver with Emphasis on the Golgi Complex as a Discrete Organelle.- Golgi Apparatus Function in Membrane Flow and Differentiation: Origin of Plasma Membrane from Endoplasmic Reticulum.- Membrane Associated Proteins.- The Conformational Model and the Structure Function Relation in Mitochondria.- ATP Synthesis in Mitochondrial Oxidative Phosphorylation.- The Transport Systems of Mitochondrial Membranes.- Spatial Orientation of the (Na++K+)-Dependent Enzymatic Reaction in the Cell Membrane.- Electric Field and Chloroplast Membranes.- Ribosome-Membrane Interaction in Eukaryotic Cells.- Uptake of Macromolecules at the Cell Surface.- The Membrane Bound Forms of Penicillinase in Bacillus Licheniformis and Their Significance for the Secretion Process.- Organization of Antigenic Structures on Cell Surfaces.- Chemistry of Specific Antigenic Sites on Cell Surfaces.- Surface Changes Detected by Lectins and Implications for Growth Regulation in Normal and in Transformed Cells.- Surface Changes and Growth of Virus Transformed Cells.- Enzymes of Bacterial Cell Wall Synthesis as Components of the Cell Membrane.- Round Table Discussion Groups.- 1. Na+-K+-Activated ATPases.- 2. Endo- and Exocytosis.- 3. Functional Aspects of Membrane Lipids.- 4. Membrane-Nucleic Acid Interactions.- 5. Nature of Membrane Alterations in Virus-Infected and Transformed Cells.
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