Synthesis of substituted phthalazine as potential antimicrobial agents

The book is an attempt to study the synthesis of heterocycles with novel chromophores as potential antimicrobial agents. The phthalazine based scaffolds having different heterocyclic chromophores includes diversity with five groups, phthalazine-methoxyacrylates, phthalazine-oxadiazoles, phthalazine-isoxazoles, phthalazine-methoxyacrylate-isoxazoles and phthalazine-triazolothiadiazole and triazolothiadiazines. Further, 114 compounds were tested for antimicrobial activity against Esherichia coli, Salmonella typhi, Bacillus subtilis and Staphylococcus aureus. The thiazole and pyridine substituted derivatives shows better activity. All the compounds were thoroughly characterized with all possible physic-chemical techniques.

Auteur

Dr. K R Venugopala Reddy is presently working as Associate Professor in Industrial Chemistry at P G Center of Sahyadri Science College, Shimoga, Karnataka, India. His current research filed is phthalocyanine chemistry and their applications for energy harvesting and bio sensing materials He has authored Six books and published more than 51 papers.