Dynamic Modeling in the Health Sciences

This book and CD-ROM integrate the use of STELLA software into the teaching of health, nutrition and physiology. The book can be used on its own as a textbook, or can serve as a supplement in nutrition and physiology courses to introduce the role that simulation modeling can play. Dynamic Modeling in the Health Sciences discusses key subjects ranging from the theory of metabolic control to weight regulation to bone metabolism, and gives readers tools to simulate these processes.

Introduces the role that simulation modeling can play in the health sciences Gives readers all the necessary tools to simulate real-world phenomena and complex problems Discusses key subjects such as gene expression, metabolic control, weight regulation, human growth and aging, bone remodeling and osteoporosis, and tumor progression

Contenu
1 Discoveries with a Computer: Dynamic behavior.- 2 How to Create STELLA® Models to Solve Basic Equations.- 3 How an Equation from Physiology Can Become a Model.- 4 Rates of Change.- 5 The Steady State: A Question of Balance.- 6 Equations for Model Building: The Surface Law and Body Composition.- 7 A Primer on Biodynamics and Gene Expression.- 8 Chronological Time Versus Physiological Time.- 9 Energy Needs for Work.- 10 The Human Thermostat.- 11 Dietary Polyunsaturated Fats and Your Cell Membranes.- 12 Responses to Nutrients.- 13 Symmetry of Human Growth and Aging.- 14 A Stochastic Model of Senescence and Demise.- 15 Mortality and Risk for Chronic Disease.- 16 Kinetic Genetics: Compartmental Models of Gene Expression.- 17 From Genotype to Phenotype.- 18 The Plateau Principle: A Key to Biological System Dynamics.- 19 Compartmental Models in Metabolic Studies: Vitamin C.- 20 Orcadian Rhythms.- 21 Diet Composition and Fat Balance.- 22 Human Cholesterol Dynamics.- 23 Stochastic Model of Bone Remodeling and Osteoporosis.- 24 Positive and Negative Feedback: Insulin and the Use of Fatty Acids and Glucose for Energy.- 25 A Multistage Model for Tumor Progression.- 26 The Biokinetic Database.- Appendix: Quick Help Guide to STELLA® Software Mechanics.