Interaction of Nanomaterials With Living Cells

This book examines the interactions of nanomaterials with the biological system. The chapters of the book explore the natural and synthetic biomaterials that modulate immune responses for their applications in drug delivery and tissue engineering. Further, the book discusses the implications of the physiochemical properties of nanoparticles and their microenvironment on their interactions with biological systems. The chapters also present the recognitive capabilities of biomaterials for the development of novel strategies for the detection and treatment of autoimmune disorders. The book also introduces nanotechnology platforms for drug delivery and highlights current and emerging nanotechnologies that could enable novel classes of therapeutics. Towards the end, the book reviews the efficiency of drug-loaded nanoparticles in modulating the functioning of the biological milieu for improved disease treatment. Lastly, the book outlines the ethical issues regarding the use of nanoparticles for in vitro and in vivo applications. Given its scope, it is a valuable resource for graduate students and researchers interested in understanding the biomedical applications of nanoparticles and their interactions with the biological milieu.

Examines the interaction of nanomaterials with biological systems Highlights the applications of nanotechnology in biomedicine Presents strategies for engineering the surface of nanoparticles for biological applications

Auteur

Dr. Faheem Arjamend Sheikh is an Assistant Professor at the Department of Nanotechnology, University of Kashmir, India (2015). He served as an Assistant Professor at the Department of Biotechnology at the Central University of Kashmir, India (2015-2016); Assistant Professor of Research at Myongji University, South Korea (2014-2015); Research Professor at Hallym University, South Korea (2012-2014); Post-Doc/Research fellow at the University of Texas Rio Grande Valley, Texas, United States of America (2010-2012) and Research Professor at Myongji University, South Korea (2010). His research mainly focuses on fabricating nanomaterials used in tissue engineering.

Currently, he is heading a lab, which works on creating different nanomaterials that can be used in various biological applications; this includes cell culturing and microbial assays. He has considerable expertise in the fabrication of polymeric, ceramic, and metal oxide nanofibers using electrospinning, as well as the production of porous materials by solvent casting, salt-leaching, 3D printing, gas forming, sol-gel synthesis, phase separation, freeze-drying, and particulate leaching and self-assembly for hard and soft tissue engineering. He has more than 16 years of research experience, focusing on tissue engineering and drug delivery. He has published more than 100 peer-reviewed articles and book chapters.

Dr. Shafquat Majeed is currently working as an Assistant Professor in the Department of Nanotechnology, University of Kashmir, India. Dr. Majeed did his Masters's in Chemistry from the Department of Chemistry, University of Kashmir. He did his Ph.D. from the Indian Institute of Science Bangalore (2008-2015). He has a postdoctoral research experience in rare-earth-based nanomaterials for biomedical applications and fabrication of Perovskite-based solar cells from the Centre for Nanoscience and Engineering, IISc Bangalore (2015-2016).

Presently, he heads a Multifunctional Nanomaterials Laboratoryat the University of Kashmir where the research group works on the synthesis, characterization, optical and magnetic properties of nanomaterials prepared through various solution-based routes.

Dr. Mushtaq A. Beigh is working as an Assistant Professor at the Department of Nanotechnology, University of Kashmir, India. Dr. Beigh has postdoctoral research experience in cellular signaling and disease modeling (2013-2016). He had completed his Ph.D. from the University of Kashmir, India (2008-2012). He heads a laboratory at the University of Kashmir, where they work on a bio-nano interface to understand the molecular basis of nanoconjugate internalization. They are working to understand the growth factor signaling inputs directed at multiple cellular receptors like NRP1 and Integrins to work out the mechanistic details of receptor-based internalization.

Contenu

Chapter 1. Role of synthetic and natural biomaterials in modulating the autoimmune response.- Chapter 2. Nanotechnology-based biosensors in medicine.- Chapter 3. Materials from natural resources for the application of bone tissue engineering.- Chapter 4. Hydroxyapatite is a next-generation theranostic probe for tissue engineering and biomedical application.- Chapter 5. Green synthesis of metallic nanoparticles and various biomedical applications.- Chapter 6. Functionalized carbon nanotube for various disease treatment.- Chapter 7. Nanotechnology: Changing the world of animal health and veterinary medicine.- Chapter 8. Bioinspired materials inherited with antimicrobial properties for tissue engineering.- Chapter 9. 3D and 4D bioprinting technology for tissue engineering applications.- Chapter 10. Hemocompatibility of differently modified polymeric nanofibers: Current progress in the biomedical industry.- Chapter 11. Polyurethane nanofibers fabricated by electrospinning as drugcarriers systems for the treatment of cancer.- Chapter 12. Recent trends in the application of materials for cancer therapy and diagnosis.- Chapter 13. Application of bioactive compounds and biomaterials in promoting cell differentiation, proliferation, and regenerating tissue.- Chapter 14. Materials for gene delivery systems.- Chapter 15. Natural hydrogels as wound dressing for skin wound healing applications.- Chapter 16. Nanomaterial applications in cancer therapy and diagnosis.- Chapter 17. Nanocellulose as a sustainable nanomaterial for films and coating layers via spray-coating and applications.- Chapter 18. Nanoparticles-based drug delivery system for beginners.- Chapter 19. Osteoarthritis: Novel insights in treatment.- Chapter 20. Promoting the Bio-potency of Bioactive Compounds through Nanoencapsulation .- Chapter 21. Review on green synthesis, modification, characterization, properties, and applications of palladium nanoparticles in biomedical applications.- Chapter 22. Innovative nanomaterials with profound antibacterial action applied in biomedical sciences.- Chapter 23. Musculoskeletal pains and its common diseases: Novel insights in treatments using biomaterials.- Chapter 24. Electrospun Cellulose and Derivatives-Based Nanofibers Loaded with Bioactive Agents for Wound Dressing Applications.- Chapter 25. Co-Delivery of Anticancer Drugs Using Polymer-Based Nanomedicines for Lung and Prostate Cancer Therapy.- Chapter 26. Silver nanoparticles incorporated textile substrate for antimicrobial applications.- Chapter 27. Recent advancement of gelatin for tissue engineering applications.- Chapter 28. Biomedical applications of the fused filament fabrication (FFF) technology.- Chapter 29. Role of Stem cells in the Delivery of Essential Pharmaceuticals.- Chapter 30. Biomaterials in autoimmune diseases.- Chapter 31. Regulatory and ethical issues raised by the utilization of nanomaterials. <p