Infectious Causes of Cancer

James J. Goedert and a team of leading experimental and clinical researchers provide critical, integrating surveys of those viruses, bacteria, and parasites that are now known to play a major role in cancer-work that opens the way toward novel therapeutic targets. The contributors focus on five types of human carcinogenic infection-herpesviruses, retroviruses, papillomaviruses, hepatitis viruses, and H. pylori-and review in depth the associated malignancies, as well as how these new diagnostic and therapeutic technologies may be implemented. Cutting-edge and cross-disciplinary, Infectious Causes of Cancer: Targets for Intervention provides clinical oncologists and infectious disease specialists, as well as clinical researchers, with insightful reviews of cancer induction by infectious diseases and the high promise of closely targeted new therapeutics and vaccines.

Includes supplementary material: sn.pub/extras

Résumé
"I found this an excellent book and a must read for any practitioner in the field or individuals involved in research within this field. The editor brings together multiple disciplines in an extremely difficult topic. I know of no other books to compare in which this topic is covered. I found the book to be exciting and accurate, with excellent coverage of each subject especially in the areas of pathogenesis and treatment modalities. It is clearly presented in a fashion that is easy to understand. I enjoyed the book thoroughly." -Doody's Health Science Book Review Journal

"The book covers all at present known types of human oncogenic infections,... This publication represents an outstanding work devoted to the current state-of-the-art of the role of viruses, bacteria, and parasites in cancer development. It gives summary of major viruses and bacteria involved in different ways in tumor induction and a comprehensive coverage of all neoplasms at present known to be caused by infectious agents. The book will prove helpful to keep us up-to-date with achievements in promising filed of targeted new cancer therapeutical and vaccines. It will be of interest both to clinical oncologist to specialists to infectious diseases and to laboratory and clinical cancer researchers." -Neoplasma

"The overall aim of this book is to review neoplasms in which certain viruses, bacteria and parasites play critical roles, anticipating that they will be the likely targets for drugs and vaccines...The book will be a valuable resource for anyone wishing to know more about the role of persistent or chronically active infection in a complex disease such as cancer...and is appropriate for a diverse group, including students of medicine, research scientists and practicing physicians and should be available in all medical libraries. It should also encourage further research in the promising field of anticancer therapy." -Folia Microbiologica

"The influence of chronic infection and inflammation on oncogenesis is also widely discussed. The volume if a treasure for reading....The book is highly recommended to all microbiologists and clinicians with an interest in aspects of the molecular pathogenesis and rational therapy of cancer." -Microbiology Today

"...the book contains timely and important information on the pathogenesis of cancer of infectious origin on the opportunities available for potentially successful intervention....the chapters are extremely well written, notably the overview chapters for retroviruses and papillomaviruses, the chapters on gastric adenocarcinoma and gall bladder cancer, and the insightful chapter on childhood leukemia." -British Medical Journal

"...this book was an exceedingly good read. A comprehensive range of associations between human cancers and infectious agents is covered and the reader is left with a very good idea of the contribution of infection to ...The book is very up-to-date and there is extensive referencing useful for further reading....I feel that this is an excellent book. For workers in the virus-cancer field, it provides a useful and comprehensive overview of this subject area that is stimulating and thought provoking. For others, outside the field, it provides an extremely good reference book from which current understanding of the infectious causation of cancer can be readily assimilated." - Hematologic Oncology

"Students, teachers, experts, and non experts will benefit from reading this book and having it close at hand for frequent reference." - Journal of the National Cancer Institute

"Infectious Causes of Cancer is intended as an introduction to infectious disease oncology for practitioners, but is also an excellent and valuable reference work of general interest to oncologists, microbiologists, and infectious disease specialists, and should be included in any medical biology or oncology library." -ASM News

Contenu
I Background.- 1 History of Infectious Disease Oncology, from Galen to Rous.- II Herpesviruses.- 2 Overview of Herpesviruses.- 3 X-Linked Lymphoproliferative Disease.- 4 Posttransplant Lymphoproliferative Disorder.- 5 Epstein-Barr Virus and Burkitt's Lymphoma.- 6 Epstein-Barr Virus and Nasopharyngeal Carcinoma.- 7 Hodgkin's Disease.- 8 AIDS-Related Lymphoma.- 9 Leiomyoma and Leiomyosarcoma.- 10 Kaposi's Sarcoma and Other HHV-8-Associated Tumors.- III Retroviruses.- 11 Retroviruses and Cancer.- 12 Adult T-Cell Leukemia/Lymphoma.- 13 Clonal HIV in the Pathogenesis of AIDS-Related Lymphoma: Sequential Pathogenesis.- IV Papillomaviruses.- 14 Papillomaviruses in Human Cancers.- 15 Anogenital Squamous Cell Cancer and Its Precursors: Natural History, Diagnosis, and Treatment.- 16 Human Papillomaviruses and Cancers of the Skin and Oral Mucosa.- V Hepatitis Viruses.- 17 Overview of Hepatitis B and C Viruses.- 18 Hepatocellular Carcinoma.- 19 Hepatitis C Virus, B-Cell Disorders, and Non-Hodgkin's Lymphoma.- VI Bacterial and Helminthic Oncology.- 20 Overview of Helicobacter pylori.- 21 Gastric Adenocarcinoma.- 22 Gastric Mucosa-Associated Lymphoid Tissue Lymphoma.- 23 Salmonella typhi/paratyphi and Gallbladder Cancer.- 24 Schistosoma hematobium and Bladder Cancer.- VII Other Infections and Human Neoplasms.- 25 Does Childhood Acute Lymphoblastic Leukemia Have an Infectious Etiology?.- 26 Polyoma Viruses (JC Virus, BK Virus, and Simian Virus 40) and Human Cancer.- 27 In Pursuit of a Human Breast Cancer Virus, from Mouse to Human.