Immunomodulatory Biomaterials and Nano-immunotherapies

Auteur
Thomas J. Webster is a Professor at the School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin, China. He is also a Visiting Professor at the Center for Biomaterials, Vellore Institute of Technology, Vellore, India and the Department of Materials Science and Engineering, Federal University of Piaui, Brazil. His degrees are in chemical engineering from the University of Pittsburgh (B.S., 1995) and in biomedical engineering from Rensselaer Polytechnic Institute (M.S., 1997; Ph.D., 2000). He has served as a professor at Purdue University (2000-2005), Brown University (2005-2012), and Northeastern University (2012-2021). He was the founding editor-in-chief of the International Journal of Nanomedicine (pioneering the open-access format). Prof. Webster has received numerous honors including: 2012, Fellow, American Institute for Medical and Biological Engineering; 2013, Fellow, Biomedical Engineering Society; 2016, International College of Fellows, Biomaterials Science and Engineering; 2016, Acta Biomaterialia Silver Award; 2019, Overseas Fellow, Royal Society of Medicine (UK); and 2022, Clarivate Most Distinguished Researcher (Top 0.1% in citations). He also served as the President of the U.S. Society For Biomaterials. Dr. Steven Zanganeh is an Assistant Professor at the New York Institute of Technology, USA. He earned his PhD in Biomedical Engineering from the University of Connecticut, USA, in 2014. He completed his postdoctoral training at Stanford University, USA, and Memorial Sloan Kettering Cancer Center in New York, USA.

Texte du rabat

Immunomodulatory Biomaterials and Nano-immunotherapies reviews the general cellular and biochemical barriers of the tumor microenvironment and other immune diseases, the ways they are addressed by modern immunotherapies, and the specific barriers facing particular immunotherapeutic approaches. The latest research on immunomodulatory biomaterials is examined, providing a perspective on their future opportunities in modulating disease treatment strategies. Translational considerations and lessons learned from the various components of nanotechnology-enabled immunotherapies, including conventional immunotherapies, nucleic acids, nanotechnology, and biotechnology-based therapeutics are assessed. Finally, a framework for the development of the next generation of nanotechnology-enabled immunotherapies is detailed, providing guidance and suggestions for those interested in the development of novel immunomodulatory nanobiomaterials. Immunomodulatory Biomaterials and Nano-immunotherapies is a key reference for researchers and developers working in biomaterials, nanotechnology, immunology, biomedical engineering and pharmaceutical sciences.

Contenu

1. What is Immunoengineering
   
   2. Immunoengineering - Drug Delivery
   3. Immunoengineering - Gene Delivery
   4. Nano-immunotherapy and Nanomedicine
   5. Cancer immunotherapy
   6. Nanotechnology-Based CAR Strategies for Tumor Immunotherapy
   7. Nano-Immunoimaging
   8. Immunoengineered Vaccines
   9. Biomaterials for Immunoengineering
   10. Chemistry of immunoengineering biomaterials
   11. Cytokine Engineering for Targeted Immunotherapy
   12. Commercialization of Nanoimunoengineering