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This book delves into the field of immobilizing biologically active and non-active molecules. It discusses the designing strategy of immobilization and the current state-of-the-art applications for advancing biomedical, agricultural, environmental and industrial practices. It focuses on aspects ranging from fundamental principles to current technological advances at multi-scale levels (macro, micro, and nano) which are suitable for cell, enzyme, and nano-catalyst based applications. Written by experts from across the globe, the contents deal with illustrated examples of molecular and cellular interactions with materials/scaffolds and discussions on factors that can affect the functionality and yield of the process. With its discussions on material science, design of delivery vehicles, separation science, additive manufacturing, agriculture and environmental science, this book will be a useful reference for researchers across multiple disciplines.
Comprehensively describes designing approaches and applications of immobilization surfaces Includes a special section on porous immobilization substrates Describes the technical aspects and engineering challenges of immobilization
Auteur
Dr. Anuj Tripathi is a scientist in the Bio-Science Group at Bhabha Atomic Research Center (BARC) and faculty at Homi Bhabha National Institute (HBNI), Mumbai, India. He completed his M.Sc. and Ph.D. in the field of Biotechnology. His doctoral study involved research on designing and applications of porous biomaterials in biomedicine and bioengineering. He has been a visiting research fellow at Newcastle University (UK), Lund University (Sweden), Kyushu University (Japan) and Protista Biotechnology AB, (Sweden). He received research fellowships/grants from different Government of India funding organizations like DBT, CSIR, DST, and from International Atomic Energy Agency (IAEA). He has published high-impact peer-reviewed research articles, book chapters, and patents in his area of research. He has edited a book with Springer Nature on the subjects Advances in Biomaterials and bulletin on Nano-biomaterials for theragnostic applications. He is an editorial board member and reviewer for several biomaterials and bioscience journals. He is a founding member of the society for interdisciplinary research in materials and biology (SIRMB) and also honored as a life member of several international science societies. His research is focused in development of novel nano-biomaterials and superabsorbent sponges by chemical and radiation chemistry for advancing the field of bioengineering, sustainable agriculture and environmental biotechnology. He has contributed significantly to cryostructurization of polymer systems and translated technologies of societal benefits.
Dr. J. S. Melo career spans over three decades in the field of research and development. He received his doctoral degree in Biochemistry from Mumbai University. He is currently the head of the "Enzyme and Microbial Technology Section" in the Bio-Science Group at the Bhabha Atomic Research Centre. He has contributed to science education as invited guestfaculty at Institute of Chemical Technology, Mumbai and as resource person at National Workshops and Refresher Courses. He is also a Professor at Homi Bhabha National Institute and associated with Mumbai University and Savitribai Phule Pune University as a Ph.D. guide. He has published over a hundred papers in peer reviewed international journals, symposiums, workshops proceedings and book chapters and is credited with an overall citation score of 3500 and h-index of 31. In the field of enzyme and microbial technology, he has developed a number of novel heterogeneous biocatalyst systems that can be used in bioprocess development, waste treatment and biosensors. Dr. Melo's current field of interest is in interdisciplinary research and nanobiotechnology for better understanding and broadening the scope of ongoing programs. Dr. Melo has been honored as a Fellow of the Maharashtra Academy of Sciences and Society of Applied Biotechnology.
Contenu
Immobilization: Then and Now.- Cell immobilization strategies for tissue engineering: Recent trends and future perspectives.- Strategies and advancement in growth factor immobilizable ECM for tissue engineering.- Prospects Of Cell Immobilization In Cancer Research And Immunotherapy.- Nano systems for repairing retinal degeneration.- Systemic drug delivery to the posterior segment of the eye: Overcoming blood-retinal barrier through smart drug design and nanotechnology.- The effects of irradiation with cold atmospheric-pressure plasma on cellular function.- Immobilization of biomolecules on plasma functionalized surfaces for biomedical applications.- A wide portray of Upconversion-nanoparticles: surface modification for bio-applications.- Advances in Amphiphilic Assemblies and its Immobilization in Room Temperature Supercooled Matrices.