From Messengers to Molecules

The decade of the brain has brought us a few steps closer to some of the key questions in neuroscience. The complexity of memory is seen on the systems and cellular level, and different types of memory are implemented in several cellular changes that can interact, or work independently.
From Messengers to Molecules: Memories are Made of These , follows the arguments from different research teams for their particular area of expertise. All chapters are written to stand-alone and provide an up-to-date introduction to the topic for both specialists and novices alike. As a result, a comprehensive compendium covering cellular mechanisms contributing to memory formation in an unusual breadth has emerged. This books will be of interest to researchers working on the pharmacology, physiology and genetics of memory formation, clinicians memory disorders, industry and students in advanced courses in Neuroscience or Pharmacology.

Contenu

Preface - Abbreviations

Section 1. Ions and Ion Channels-Calcium-Potassium

Section 2. Principle Neurotransmitters- Glutamate Receptors - ã-Amino-Butyric Acid (GABA)- Acetylcholine: I. Muscarinic Receptors - Acetylcholine: II. Nicotinic Receptors- Serotonin - Dopamine - Adrenaline and Noradrenaline- Histamine - Adenosine and Purines

Section 3. Neuromodulators- Cannabinoids - Opioids - Neuropeptides - Nerve Growth Factors and Neurotrophins - Eph Receptors and Their Ephrin Ligands in Neural Plasticity- Corticosteroids

Section 4. Second Messengers and Enzymes- Adenylyl Cyclases - Phospholipases and Oxidases - Protein Kinase A - Protein Kinase C - CaMKinase II - MAP Kinases - Phosphatases - Nitric Oxide

Section 5. Transcription Factors, Genes and Proteins- CREB - Immediate-Early Genes - Protein Synthesis: I. Pharmacology - Protein Synthesis: II. New Proteins

Section 6. Morphological Changes in Synapses and Neurones- Learning-Induced Synaptogenesis and Structural Synaptic Remodeling - Cell Adhesion Molecules

Section 7. Learning about Memory by Studying Brain Dysfunction- Animal and Human Amnesia: The Cholinergic Hypothesis Revisited - Aging and the Calcium Homeostasis

Index