Delta Opioid Receptor Pharmacology and Therapeutic Applications

Discusses emerging knowledge about the biological function of the delta opioid receptor

Describes therapeutic potential of the delta opioid receptor system

Describes unique trafficking and signaling properties of the delta opioid receptor

Contenu
Part 1. DOPR Ligands .- 1. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept.- 2. Multifunctional Opioid Ligands.- 3. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins.- Part 2. DOPR Signaling .- 4. Ligand-Directed Signaling at the Delta Opioid Receptor.- 5. Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons.- 6. Evidence and Function Relevance of Native DORMOR Heteromers.- Part 3. DOPR and Disease .- 8. The Delta Opioid Receptor in Pain Control.- 9. Delta Opioid Receptors and Modulation of Mood and Emotion.- 10. Delta Opioid Pharmacology in Relation to Alcohol Behaviors.- 11. Delta Opioid Receptors: Learning and Motivation.- 12. Delta Opioid Pharmacology in Parkinson's Disease.- 13. Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders.-14. Delta Opioid Receptors and Cardioprotection.- 15. The Roles of Opioid Receptors in Cutaneous Wound Healing.