Brain and Heart Dynamics

An ambitious and comprehensive manual on the brain-heart dialogue an innovative and highly relevant topic.

International opinion leaders present a wide range of perspectives: from social and philosophical aspects to neurological implications.

Appeals to a broad readership with dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists. Proposes new approaches to study the brain-heart dialogue, e.g. in relation to gender.

Offers insightful approach to neuro-cardiovascular disease Presents diverse perspectives, from social to neurological Proposes new approaches to study the brain-heart dialogue Includes supplementary material: sn.pub/extras

Auteur

Stefano Govoni born in Milano, Italy, in 1950, is Full Professor of Pharmacology in the Department of Drug Sciences at the University of Pavia. He has worked in various Italian Universities (Bari, Brescia, Milano, Pavia) and back in 197981 at NIMH, St. Elizabeths hospital, Washington, D.C.

At the University of Pavia he has been director of the Department of Experimental and Applied Pharmacology, President of the Evaluation Office, Chancellor's Deputy for teaching activities, and Vice-Chancellor. Stefano Govoni has been Consultant for Biological Research Programs, Alzheimer Unit, FBF Hospital, Brescia; member of various ethical committees; and director of the Bioethical Committee of the San Matteo Hospital in Pavia, Italy.

Stefano Govoni has worked on brain aging and on Alzheimer's disease (AD) contributing to the definition of the neurobiology and physiology of beta amyloid and to the characterization of the antidementia drugs. In 2010, together with Emilio Vanoli, he started a search on the role of NGF in heart disease and is co-founder of a spin-off Neuheart working within this field. Recently he started a search on the therapeutic appropriateness of drugs used in nursing homes and in the elderly. In the period 20002011 he has been the national coordinator of a group of six laboratories belonging to various Italian universities (Pavia, Genoa, Catania, Florence, Foggia, Palermo) working on AD.

Stefano Govoni is author of more than 330 papers listed in Medline and some 20 books.

Pierluigi Politi is Full Professor of Psychiatry at the University of Pavia, Italy, and Head of Mental Health and Dependencies Department of ASST Pavia, the Regional Health Trust in Italy, and Head of the Specialization School in Psychiatry. He is also member of tEACH, the didactic subunit of International Association for Communication in Healthcare, and Full Member of the International Psychoanalytical Association.

His interest in heart and brain dynamics dates back to his Ph.D. years, when he supported the heart transplantation team at Pavia, Policlinico San Matteo Foundation; he provided evaluation of the candidates and follow-up of more than one thousand recipients. More recently, he focused his research and clinical work on autism spectrum disorders, through an intense cooperation with Cascina Rossago, the first Italian farmcommunity tailored for low-functioning people with autism. He thus developed bench to bedside research, besides new strategies of intervention, becoming a point of reference for the special talents in autism spectrum disorders. He also promoted some innovative job opportunities and a better quality of life in people belonging to this condition.

He authored/coauthored/edited 14 books, many books chapters, and some 140 papers on peer-reviewed journals. Being also an amateur jazz musician, he founded the Orchestra Invisibile (https://en.wikipedia.org/wiki/Orches tra_Invisibile) in 2005, a large jazz band, where one half of musicians belong to the autism spectrum condition.

Emilio Vanoli Graduated in Medicine with laude and specialization in Cardiology at the University of Milano. He has been involved in basic science and clinical research on autonomic nervous system cardiac control since his 4th year med school. Emilio was trained at the Centro Fisiologia Clinica and Ipertensione at the University of Milano, and he developed his research at the Department of Physiology at the University of Oklahoma HSC where he reached the position of adjunct Associate Professor of physiology and cardiology.

His major achievement here was the first experimental evidence of feasibility and efficacy of chronic implantable vagal stimulation in ischemic heart disease. Emilio is author and/or coauthor of 96 full-length papers and editor of 3 books. He is currently teaching at the International Harvey School of Medicine at the University of Pavia as Associate Professor of Cardiology in the Department of Molecular Medicine. He is sharing with Prof. Govoni the scienti fic direction of the academic spin-off named Neu-Heart whose first mission is active research on the Nerve Growth Factor (NGF). Clinically wise, he practiced as family doctor for 13 years in the Italian public healthcare system. Emilio was member of the intensive Coronary Care Unit staff at the IRCCS San Matteo Hospital in Pavia. He established his role in the area of autonomic treatment of heart failure as member of CIBIS II and III trials event committee.

Emilio is currently director of the outpatients Heart Failure Clinic at the IRCCS MultiMedica in Sesto San Giovanni (reference Cardiovascular Clinical Research Center for the Italian Ministry of Health Care) supported by extensive public funding to implement remote home monitoring of fragile patients.

Contenu
Section 1: Functional Anatomy and Molecular Basis of the Cardiac-Brain Axis. Section 2: Inflammatory Processes Perturbing Brain-Heart DialogueSection 3: Emotional Processes and How They May Influence Cardiovascular Activity, Disease Onset, Outcomes and Quality of Life. Section 4: Bidirectional Influences of Common Psychiatric Conditions and Cardiovascular ActivitySection 5: Neurological Diseases and How they may influence Cardiovascular activity, disease Onset, outcomes and Quality of Life.Section 6: Sleep and HeartSection 7: Pain and HeartSection 8: Drugs used in Psychiatry and Neurology Affecting Cardiovascular Activity and Cardiovascular Drugs Producing Neuropsychiatric Alternations. Section 9: Drugs of Abuse and Cardiovascular FunctionSection 10: Lifestyle and Activities influencing cardiovascular and Cerebral Function.Section 11: Gender and Age Differences Affecting Brain and Heart connection.