Biochemical Techniques for Analyzing Protein-Lipid Interactions

The book reviews cutting-edge advancements and their implications across various domains of molecular diagnostics. It covers foundational topics like protein-ligand interactions, lipid-protein interactions within biological membranes, and the application of NMR spectroscopy in understanding membrane structures. The book also explores advanced techniques such as X-ray crystallography, liposome microarray assays, and protein-lipid interaction studies. By integrating experimental and computational methods, it provides a comprehensive guide to understanding the complexities of molecular diagnostics, from basic principles to innovative approaches in drug discovery and therapeutic development. Each chapter offers detailed discussions on specific topics, supported by experimental data and methodological insights, making it an invaluable resource for researchers, clinicians, and students seeking to enhance their knowledge and expertise in molecular diagnostics.

Presents the landscape of protein-ligand interactions Covers the traditional and emerging techniques for studying the protein-ligand interactions Discusses challenges and opportunities for analyzing protein-ligand interactions

Auteur

Dr. Ayub Ali Patel is working as Assistant Professor at King Khalid University, Abha, KSA. He is involved in the Students' Advisory Committee and is a member of the Saudi Society for Medical Education. An active member of the College of Medicine Medical Education department and assessment unit. Previously, he was a Postdoctoral Fellow at the University of St. Andrews, ST ANDREWS, Scotland and the University of Dundee, DUNDEE, Scotland, UK, and the University of Bern, BERN, Switzerland. His research was focused on the preparation of new precursors for MOVPE growth of (Hg, Cd)Te. Preparation of suitable alkylHgI and alkylAs precursors for doping CMT and their volatility and decomposition properties by GCMS. Till now, he has published more than 50 articles in peer review international journals.

Contenu

Chapter 1. Challenges and opportunities for analyzing protein-ligand interactions.- Chapter 2. The Landscape of Lipid Protein Interaction.- Chapter 3. NMR Spectroscopy.- Chapter 4. X-ray crystallography.- Chapter 5. Lipisome microarray based assay.- Chapter 6. protein-lipid overlay assay.- Chapter 7. Quantitative Analysis of Protein-Lipid Interactions Using Tryptophan Fluorescence.- Chapter 8. Liposome Sedimentation Assay.- Chapter 9. Affinity purification lipodomics.- Chapter 10. Advanced Techniques for Analyzing The Protein-Lipid Interactions.