Calcium Phosphate Nanocoatings for Bone Regeneration

This book provides in-depth assessment on the latest clinical advances in multifunctional calcium phosphate nanocoatings and its influence on bone regeneration and early healing following implantation. A greater emphasis will be placed on the use of nanocomposite coatings to deliver biological materials such as mesenchymal stem cells, growth factors, bone morphogenetic and extracellular matrix proteins, and pharmaceutics such as simvastatin to improve and promote bone growth as well as reducing the timeframe needed for implant integration in both healthy and osteoporotic patients. The content of the book caters to clinical practitioners and researchers working in the field of biomaterials for bone regeneration.

Presents calcium phosphate as a coating material for dental and orthopedic applications Assesses clinical advances on bone regeneration and early healing following implantation Describes the incorporation of biological materials, osteogenic agents, and pharmaceuticals

Auteur

Dr. Andy H. Choi is an early career researcher who received his Ph.D. from the University of Technology Sydney (UTS) in Australia in 2004 on the use of computer modeling and simulation known as finite element analysis (FEA) to examine the biomechanical behavior of implants installed into a human mandible. After completing his Ph.D., he expanded his research focus from FEA to sol gel synthesis of multifunctional calcium phosphate nano-coatings and nanocomposite coatings for dental and biomedical applications. In late 2010, Dr. Choi was successfully awarded the internationally competitive Endeavour Australia Cheung Kong Research Fellowship Award and undertook postdoctoral training at the Faculty of Dentistry of the University of Hong Kong focusing on the application of FEA in dentistry and the development of calcium phosphate nano-bioceramics. He is currently serving as an associate editor for the Journal of the Australian Ceramic Society and as an editor for a number of dentistry-related journals. In addition, he is also serving as an editorial board member for several dentistry, nanotechnology, and orthopedics journals. To date, Dr. Choi has published over 50 publications including 6 books and 30 chapters on calcium phosphate, nano-biomaterial coatings, sol gel technology, marine structures, drug delivery, tissue engineering, and finite element analysis in nanomedicine and dentistry.
Professor Besim Ben-Nissan has higher degrees in Metallurgical and Materials Engineering (ITU), Ceramic Engineering (University of New South Wales), and a Ph.D. in Mechanical and Industrial Engineering Biomedical Engineering (University of New South Wales). Over the last four decades together with a large numbers of Ph.D. students and postdoctoral fellows and surgeons, he has worked on production and analysis of various biomedical materials, implants, slow drug delivery devices, calcium phosphate ceramics, advanced ceramics (alumina, zirconia, silicon nitrides), sol gel developed nanocoatings for enhanced bioactivity, antimicrobial coatings, corrosion and abrasion-resistant coatings, optical and electronic ceramics, and thermally insulating new generation composites.
After serving as an academic for over 33 years, he has retired from teaching, however, still is active and contributes to science by research in the translational medicine, biomedical field, and supervising of higher degree students.

Contenu
Introduction.- Why Surface Modification.- Calcium Phosphate.- Mechanical Integrity of Thin Films and Coatings and their Clinical Significance.- Coating Deposition Techniques.- Cellular Responses.- Enhancing Implant Osseointegration through Nanocomposite Coatings.- Calcium Phosphate Nanocoated Coralline Apatite.