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This volume covers the current status of research in the neurobiology of motivated behaviors in humans and other animals in healthy condition. This includes consideration of the psychological processes that drive motivated behavior and the anatomical, electrophysiological and neurochemical mechanisms which drive these processes and regulate behavioural output. The volume also includes chapters on pathological disturbances in motivation including apathy, or motivational deficit as well as addictions, the pathological misdirection of motivated behavior. As with the chapters on healthy motivational processes, the chapters on disease provide a comprehensive up to date review of the neurobiological abnormalities that underlie motivation, as determined by studies of patient populations as well as animal models of disease. The book closes with a section on recent developments in treatments for motivational disorders.
The most comprehensive and up to date book covering the neurobiology of motivation The neurobiology of motivation in both health and disease will be equally covered by including research findings from healthy subjects, humans and other animals, as well as research involving clinical patients and animal models of disease processes Focus on translational crossover provided by clinical and pre-clinical researchers in the field Includes supplementary material: sn.pub/extras
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Part 1.- THE NEUROBIOLOGY OF COMPONENTS OF MOTIVATIONAL DRIVE.- Regulation of the Motivation to Eat.- Sexual Motivation Opposed by the Influences of Stress .- Motivational Forces Driving Social Behaviours.- The Roles of Wanting and Liking in Motivating Behaviour, Including Gambling, Food and Drug Addiction. Circadian Regulation of Motivated Behaviour.- How Negative Forces Influence Motivations Part 2.- NEURAL MEASURES AND CORRELATES OF MOTIVATION SIGNALS AND COMPUTATIONS.- Neural Computations of Postive and Negative Reward Value.- The Dopaminergic Regulation of Motivated Behaviour.- Neural Modulators other than Dopamine that Regulate Motivated Behaviours.- Neural Correlates of Motivation Signals in Humans.- Motivational Forces in Decision Making Processes.- Part 3.- APATHY AND PATHOLOGICAL DEFICITS IN MOTIVATION.- The Identification of Phenotypes and Biomarkers in Depression.- Defining Motivation Deficits in Schizophrenia and Relating them to Clinical Symptoms.- Dissecting the Behavioural components of deficits in motivation in Patients with Schizophrenia.- How Deficits in Motivation are Similar and Different in Depression and Schizophrenia.- Modeling Motivation Deficits in Rodents .- Part 4.- ADDICTION AND THE APTHOLOGICAL MISDIRECTION OF MOTIVATED BEHAVIOUR.- Motivation in Overdrive: Substance Abuse Disorder.- Insight into Gambling motivation from Animal Models.- Part 5.- DEVELOPMENTS IN TREATMENTS FOR MOTIVATION PATHOLOGIES.- The Role of Motivation in Schizophrenia Cognitive Remediation.- The Impact of Regulating Focus on Motivated Behaviour.- Insights into Gambling Motivation from Animal Models.- Exploring Pharmacological Agents in Animal Models.
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