Cardiovascular Genetics and Genomics

This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic. Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this rapidly developing field.

Autorentext
Dan M. Roden, M.D., Professor of Medicine and Pharmacology, Director, Oates Institute for Experimental Therapeutics, Assistant Vice-Chancellor for Personalized Medicine, Vanderbilt University School of Medicine.

Inhalt

Provisional list of contents.

Section A: Principles.

1 Principles of genetics and genomics.

2 Candidate gene and genome-wide association approaches.

3 A primer in statistical methods in genetics.

4 Ethical, legal, and social issues.

5 The role of ethnicity in managing cardiovascular patients.

6 Moving to the bedside: When? How?.

Section B: Specific cardiovascular disease.

7 Genomics and Atrial Arrhythmias.

8 Ventricular arrhythmias and sudden death.

9 Hypertrophic Cardiomyopathy and Other Forms of
Hypertrophy.

10 Genetics and genomics of dilated cardiomyopathy.

11 Arrhythmogenic Right Ventricular Cardiomyopathy.

12 Genetics of atherosclerosis.

13 Hypertension.

14 Stroke Genomics.

15 Thrombosis.

16 Case study: warfarin pharmacogenetics from single to multiple
genes.

17 Pharmacogenetics and Pharmacogenomics.