NEW! Global conditions of importance are covered, including those previously not discussed, that exist in Europe, Central and South America, Australia, and New Zealand.
NEW! Coverage of emerging and re-emerging diseases includes the new pathogen discovery.
NEW! Assessment of vaccination status and susceptibility to infection discusses how antibody titers can predict protection for some pathogens.
NEW! Description of epigenetics and metagenomics provides detailed coverage of these emerging areas of interest.
NEW! Table of zoonoses obtained from large animals includes symptoms and disinfection needs.
NEW! Coverage of genetic disorders, Hydrocephalus in Fresians and Pulmonary hypoplasia with Anasarca in Dexter cattle help you to treat these disorders.
NEW! Extensively updated content clarifies the latest research and clinical findings on the West Nile Virus, therapeutic drug monitoring, muscle disorders, GI microbiota, the genetic basis for Immune-mediated myositis in Quarter Horses, discoveries in antimicrobial drugs, anthelmintic, and vaccines, and more!

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PART I: HISTORY, PHYSICAL EXAMINATION, AND MEDICAL RECORDS 1. Ruminant History, Physical Examination, and Records 2. Equine History, Physical Examination, Records, and Recognizing Abuse or Neglect in Patients PART II: MANIFESTATIONS OF DISEASE 3. Pain 4. Alterations in Body Temperature 5. Alterations in Respiratory Function 6. Alterations in Cardiovascular and Hemolymphatic Systems 7. Alterations in Alimentary and Hepatic Function 8. Localization and Differentiation of Neurologic Diseases 9. Alterations in Body Weight or Size 10. Alterations in Urinary Function 11. Alterations in the Skin 12. Alterations in Sexual Function 13. Musculoskeletal Abnormalities 14. Collapse and Sudden Death PART III: DISORDERS AND MANAGEMENT OF THE NEONATE 15. The Equine Peripartum Period 16. Assessment of the Newborn Foal 17. Manifestations and Management of Disease in Neonatal Foals 18. The Peripartum Ruminant 19. Initial Management and Clinical Investigation of Neonatal Ruminants 20. Manifestations and Management of Disease in Neonatal Ruminants 21. Colostrum and Milk Replacers PART IV: COLLECTION OF SAMPLES AND INTERPRETATION OF LABORATORY TESTS 22. Clinical Chemistry Tests 23. Collection and Submission of Samples for Hematologic and Cytologic Studies 24. Alterations in the Erythron 25. Alterations in the Leukogram 26. Alterations in Blood Proteins 27. Alterations in Hemostasis 28. Collection and Analysis of Bone Marrow 29. Molecular Diagnostics PART V: DISORDERS OF THE ORGAN SYSTEMS 30. Diseases of the Cardiovascular System 31. Diseases of the Respiratory System 32. Diseases of the Alimentary Tract 33. Diseases of Hepatobiliary System 34. Diseases of the Renal System 35. Diseases of the Nervous System 36. Mammary Gland Health 37. Diseases of the Hematopoietic and Hemolymphatic Systems 38. Diseases of the Bones, Joints, and Connective Tissues 39. Diseases of the Eye 40. Diseases of the Skin 41. Endocrine and Metabolic Diseases 42. Diseases of Muscle 43. Diseases of the Reproductive System PART VI: PREVENTIVE AND THERAPEUTIC STRATEGIES 44. Critical Care and Fluid Therapy 45. Rational Antimicrobial Therapy 46. Biosecurity and Infection Control 47. Prevention, Detection, and Response to Transboundary (Foreign) Animal Diseases 48. Use of Biologics in the Prevention of Infectious Diseases 49. Parasite Control Programs 50. Nutrition of the Sick Animal PART VII: CONGENTIAL, HEREDITARY, IMMUNOLOGIC, AND TOXIC DISORDERS 51. Genetic Disorders 52. Genetic Tests for Large Animals 53. Immunologic Disorders 54. Disorders Caused by Toxicants